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Porin-Mediated Antibiotic Resistance in Neisseria gonorrhoeae: Ion, Solute, and Antibiotic Permeation through PIB Proteins with penB Mutations

Neisseria gonorrhoeae has two porins, PIA and PIB, whose genes (porA and porB, respectively) are alleles of a single por locus. We recently demonstrated that penB mutations at positions 120 and 121 in PIB, which are presumed to reside in loop 3 that forms the pore constriction zone, confer intermedi...

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Detalhes bibliográficos
Main Authors: Olesky, Melanie, Zhao, Shuqing, Rosenberg, Robert L., Nicholas, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428387/
https://ncbi.nlm.nih.gov/pubmed/16547016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.7.2300-2308.2006
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