Crystal structure of Pistol, a class of self-cleaving ribozyme

מאת Nguyen, Laura A., Wang, Jimin, Steitz, Thomas A.
הוצא לאור ב Proc Natl Acad Sci U S A (2017)

Tight Interplay among SAMHD1 Protein Level, Cellular dNTP Levels, and HIV-1 Proviral DNA Synthesis Kinetics in Human Primary Monocyte-derived Macrophages

מאת Kim, Baek, Nguyen, Laura A., Daddacha, Waaqo, Hollenbaugh, Joseph A.
יצא לאור 2012

Effect of Ribonucleotides Embedded in a DNA Template on HIV-1 Reverse Transcription Kinetics and Fidelity

מאת Daddacha, Waaqo, Noble, Erin, Nguyen, Laura A., Kennedy, Edward M., Kim, Baek
יצא לאור 2013

Altered Strand Transfer Activity of a Multi-drug-resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutant with a Dipeptide Fingers Domain Insertion

מאת Nguyen, Laura A., Daddacha, Waaqo, Rigby, Sean, Bambara, Robert A., Kim, Baek
יצא לאור 2011

SAMHD1 Restricts HIV-1 Replication and Regulates Interferon Production in Mouse Myeloid Cells

מאת Zhang, Ruonan, Bloch, Nicolin, Nguyen, Laura A., Kim, Baek, Landau, Nathaniel R.
יצא לאור 2014

HIV-1 Reverse Transcriptase dissociates during strand transfer

מאת Muchiri, John M., Rigby, Sean T., Nguyen, Laura A., Kim, Baek, Bambara, Robert A.
יצא לאור 2011

Host SAMHD1 Protein Promotes HIV-1 Recombination in Macrophages

מאת Nguyen, Laura A., Kim, Dong-Hyun, Daly, Michele B., Allan, Kevin C., Kim, Baek
יצא לאור 2014

Host SAMHD1 protein promotes HIV-1 recombination in macrophages.

מאת Nguyen, Laura A., Kim, Dong-Hyun, Daly, Michele B., Allan, Kevin C., Kim, Baek
יצא לאור 2014

Pre-steady State Kinetic Analysis of HIV-1 Reverse Transcriptase for Non-canonical Ribonucleoside Triphosphate Incorporation and DNA Synthesis from Ribonucleoside-containing DNA Te...

מאת Nguyen, Laura A., Domaoal, Robert A., Kennedy, Edward M., Kim, Dong-Hyun, Schinazi, Raymond F., Kim, Baek
הוצא לאור ב Antiviral Res (2014)

Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors

מאת Yang, Yang, Kang, Dongwei, Nguyen, Laura A, Smithline, Zachary B, Pannecouque, Christophe, Zhan, Peng, Liu, Xinyong, Steitz, Thomas A
הוצא לאור ב eLife (2018)

Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect

מאת Bhattacharya, Akash, Wang, Zhonghua, White, Tommy, Buffone, Cindy, Nguyen, Laura A., Shepard, Caitlin N., Kim, Baek, Demeler, Borries, Diaz-Griffero, Felipe, Ivanov, Dmitri N.
הוצא לאור ב Sci Rep (2016)

Functionality of Redox-Active Cysteines Is Required for Restriction of Retroviral Replication by SAMHD1

מאת Wang, Zhonghua, Bhattacharya, Akash, White, Tommy, Buffone, Cindy, McCabe, Aine, Nguyen, Laura A., Shepard, Caitlin N., Pardo, Sammy, Kim, Baek, Weintraub, Susan T., Demeler, Borries, Diaz-Griffero, Felipe, Ivanov, Dmitri N.
הוצא לאור ב Cell Rep (2018)

SAMHD1 prevents autoimmunity by maintaining genome stability

מאת Kretschmer, Stefanie, Wolf, Christine, König, Nadja, Staroske, Wolfgang, Guck, Jochen, Häusler, Martin, Luksch, Hella, Nguyen, Laura A, Kim, Baek, Alexopoulou, Dimitra, Dahl, Andreas, Rapp, Alexander, Cardoso, M Cristina, Shevchenko, Anna, Lee-Kirsch, Min Ae
הוצא לאור ב Ann Rheum Dis (2015)

Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response

מאת Behrendt, Rayk, Schumann, Tina, Gerbaulet, Alexander, Nguyen, Laura A., Schubert, Nadja, Alexopoulou, Dimitra, Berka, Ursula, Lienenklaus, Stefan, Peschke, Katrin, Gibbert, Kathrin, Wittmann, Sabine, Lindemann, Dirk, Weiss, Siegfried, Dahl, Andreas, Naumann, Ronald, Dittmer, Ulf, Kim, Baek, Mueller, Werner, Gramberg, Thomas, Roers, Axel
הוצא לאור ב Cell Rep (2013)

Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells

מאת Baldauf, Hanna-Mari, Stegmann, Lena, Schwarz, Sarah-Marie, Ambiel, Ina, Trotard, Maud, Martin, Margarethe, Burggraf, Manja, Lenzi, Gina M., Lejk, Helena, Pan, Xiaoyu, Fregoso, Oliver I., Lim, Efrem S., Abraham, Libin, Nguyen, Laura A., Rutsch, Frank, König, Renate, Kim, Baek, Emerman, Michael, Fackler, Oliver T., Keppler, Oliver T.
הוצא לאור ב Proc Natl Acad Sci U S A (2017)