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HIV-1 Reverse Transcriptase dissociates during strand transfer

Steps in the replication of HIV-1 occurring in the virus, but not the host are preferred targets of anti-retroviral therapy. Strand transfer is unique; the DNA strand being made by viral reverse transcriptase (RT) is moved from one RNA template position to another.(1) Understanding the mechanism req...

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Autori principali: Muchiri, John M., Rigby, Sean T., Nguyen, Laura A., Kim, Baek, Bambara, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166975/
https://ncbi.nlm.nih.gov/pubmed/21821047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.07.055
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