Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors.

Reverse transcriptase must perform two specialized template switches during retroviral DNA synthesis. Here, we used Moloney murine leukemia virus-based vectors to examine the site of one of these switches during intracellular reverse transcription. Consistent with original models for reverse transcr...

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Autores principales: Kulpa, D, Topping, R, Telesnitsky, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169686/
https://ncbi.nlm.nih.gov/pubmed/9049314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.4.856
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