The EP3 Receptor: Exploring a New Target for Type 2 Diabetes Therapeutics

by Neuman, Joshua C., Kimple, Michelle E.
Published in J Endocrinol Diabetes Obes (2013)

Dietary polyunsaturated fatty acids and their metabolites: Implications for diabetes pathophysiology, prevention, and treatment

by Neuman, Joshua C., Fenske, Rachel J., Kimple, Michelle E.
Published in Nutr Healthy Aging (2017)

Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes

by Kimple, Michelle E, Neuman, Joshua C, Linnemann, Amelia K, Casey, Patrick J
Published 2014

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination

by Neuman, Joshua C., Truchan, Nathan A., Joseph, Jamie W., Kimple, Michelle E.
Published 2014

Low‐density lipoprotein receptor is required for cholesteryl ester transfer protein to regulate triglyceride metabolism in both male and female mice

by Palmisano, Brian T., Yu, Sophia, Neuman, Joshua C., Zhu, Lin, Luu, Thao, Stafford, John M.
Published in Physiol Rep (2021)

A single-islet microplate assay to measure mouse and human islet insulin secretion

by Truchan, Nathan A, Brar, Harpreet K, Gallagher, Shannon J, Neuman, Joshua C, Kimple, Michelle E
Published in Islets (2015)

Glucagon-Like Peptide-1 Regulates Cholecystokinin Production in β-Cells to Protect From Apoptosis

by Linnemann, Amelia K., Neuman, Joshua C., Battiola, Therese J., Wisinski, Jaclyn A., Kimple, Michelle E., Davis, Dawn Belt
Published in Mol Endocrinol (2015)

Cholesteryl Ester Transfer Protein Impairs Triglyceride Clearance via Androgen Receptor in Male Mice

by Palmisano, Brian T., Anozie, Uche, Yu, Sophia, Neuman, Joshua C., Zhu, Lin, Edington, Emery M., Luu, Thao, Stafford, John M.
Published in Lipids (2020)

Bombesin preserves goblet cell resistin-like molecule beta during parenteral nutrition, but not other goblet cell products

by Busch, Rebecca A., Heneghan, Aaron F., Pierre, Joseph F., Neuman, Joshua C., Reimer, Claire A., Wang, Xinying, Kimple, Michelle E., Kudsk, Kenneth A.
Published in JPEN J Parenter Enteral Nutr (2015)

Prostaglandin E(2) Receptor, EP3, Is Induced in Diabetic Islets and Negatively Regulates Glucose- and Hormone-Stimulated Insulin Secretion

by Kimple, Michelle E., Keller, Mark P., Rabaglia, Mary R., Pasker, Renee L., Neuman, Joshua C., Truchan, Nathan A., Brar, Harpreet K., Attie, Alan D.
Published 2013

Hepatocyte Small Heterodimer Partner Mediates Sex-Specific Effects on Triglyceride Metabolism via Androgen Receptor in Male Mice

by Palmisano, Brian T., Zhu, Lin, Litts, Bridget, Burman, Andreanna, Yu, Sophia, Neuman, Joshua C., Anozie, Uche, Luu, Thao N., Edington, Emery M., Stafford, John M.
Published in Metabolites (2021)

Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding

by Zhu, Lin, Shi, Jeanne, Luu, Thao N., Neuman, Joshua C., Trefts, Elijah, Yu, Sophia, Palmisano, Brian T., Wasserman, David H., Linton, MacRae F., Stafford, John M.
Published in Mol Metab (2017)

Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system

by Arriola Apelo, Sebastian I., Neuman, Joshua C., Baar, Emma L., Syed, Faizan A., Cummings, Nicole E., Brar, Harpreet K., Pumper, Cassidy P., Kimple, Michelle E., Lamming, Dudley W.
Published in Aging Cell (2015)

Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion

by Sandhu, Harpreet K., Neuman, Joshua C., Schaid, Michael D., Davis, Sarah E., Connors, Kelsey M., Challa, Romith, Guthery, Erin, Fenske, Rachel J., Patibandla, Chinmai, Breyer, Richard M., Kimple, Michelle E.
Published in Pharmacol Res Perspect (2021)

Agonist-independent Gα(z) activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes

by Schaid, Michael D., Green, Cara L., Peter, Darby C., Gallagher, Shannon J., Guthery, Erin, Carbajal, Kathryn A., Harrington, Jeffrey M., Kelly, Grant M., Reuter, Austin, Wehner, Molly L., Brill, Allison L., Neuman, Joshua C., Lamming, Dudley W., Kimple, Michelle E.
Published in J Biol Chem (2020)

Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E(2) Signaling and Enhances Diabetic β-Cell Function

by Neuman, Joshua C., Schaid, Michael D., Brill, Allison L., Fenske, Rachel J., Kibbe, Carly R., Fontaine, Danielle A., Sdao, Sophia M., Brar, Harpreet K., Connors, Kelsey M., Wienkes, Haley N., Eliceiri, Kevin W., Merrins, Matthew J., Davis, Dawn B., Kimple, Michelle E.
Published in Diabetes (2017)

The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition

by Pierre, Joseph F., Neuman, Joshua C., Brill, Allison L., Brar, Harpreet K., Thompson, Mary F., Cadena, Mark T., Connors, Kelsey M., Busch, Rebecca A., Heneghan, Aaron F., Cham, Candace M., Jones, Elaina K., Kibbe, Carly R., Davis, Dawn B., Groblewski, Guy E., Kudsk, Kenneth A., Kimple, Michelle E.
Published in Am J Physiol Gastrointest Liver Physiol (2015)

Phenotypic Characterization of MIP-CreERT(1Lphi) Mice With Transgene-Driven Islet Expression of Human Growth Hormone

by Oropeza, Daniel, Jouvet, Nathalie, Budry, Lionel, Campbell, Jonathan E., Bouyakdan, Khalil, Lacombe, Julie, Perron, Gabrielle, Bergeron, Valerie, Neuman, Joshua C., Brar, Harpreet K., Fenske, Rachel J., Meunier, Clemence, Sczelecki, Sarah, Kimple, Michelle E., Drucker, Daniel J., Screaton, Robert A., Poitout, Vincent, Ferron, Mathieu, Alquier, Thierry, Estall, Jennifer L.
Published in Diabetes (2015)

Systemic Metabolic Alterations Correlate with Islet-Level Prostaglandin E(2) Production and Signaling Mechanisms That Predict β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes...

by Schaid, Michael D., Zhu, Yanlong, Richardson, Nicole E., Patibandla, Chinmai, Ong, Irene M., Fenske, Rachel J., Neuman, Joshua C., Guthery, Erin, Reuter, Austin, Sandhu, Harpreet K., Fuller, Miles H., Cox, Elizabeth D., Davis, Dawn B., Layden, Brian T., Brasier, Allan R., Lamming, Dudley W., Ge, Ying, Kimple, Michelle E.
Published in Metabolites (2021)

Decreased consumption of branched chain amino acids improves metabolic health

by Fontana, Luigi, Cummings, Nicole E., Arriola Apelo, Sebastian I., Neuman, Joshua C., Kasza, Ildiko, Schmidt, Brian A., Cava, Edda, Spelta, Francesco, Tosti, Valeria, Syed, Faizan A., Baar, Emma L., Veronese, Nicola, Cottrell, Sara E., Fenske, Rachel J., Bertozzi, Beatrice, Brar, Harpreet K., Pietka, Terri, Bullock, Arnold D., Figenshau, Robert S., Andriole, Gerald L., Merrins, Matthew J., Alexander, Caroline M., Kimple, Michelle E., Lamming, Dudley W.
Published in Cell Rep (2016)