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Glucagon-Like Peptide-1 Regulates Cholecystokinin Production in β-Cells to Protect From Apoptosis

Cholecystokinin (CCK) is a classic gut hormone that is also expressed in the pancreatic islet, where it is highly up-regulated with obesity. Loss of CCK results in increased β-cell apoptosis in obese mice. Similarly, islet α-cells produce increased amounts of another gut peptide, glucagon-like pepti...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Linnemann, Amelia K., Neuman, Joshua C., Battiola, Therese J., Wisinski, Jaclyn A., Kimple, Michelle E., Davis, Dawn Belt
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484781/
https://ncbi.nlm.nih.gov/pubmed/25984632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1030
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