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Interleukin 6 protects pancreatic β cells from apoptosis by stimulation of autophagy
IL-6 is a pleiotropic cytokine with complex roles in inflammation and metabolic disease. The role of IL-6 as a pro- or anti-inflammatory cytokine is still unclear. Within the pancreatic islet, IL-6 stimulates secretion of the prosurvival incretin hormone glucagon-like peptide 1 (GLP-1) by α cells an...
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| Pubblicato in: | FASEB J |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Federation of American Societies for Experimental Biology
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5572685/ https://ncbi.nlm.nih.gov/pubmed/28592636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700061RR |
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