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Pancreatic beta cell autophagy is impaired in type 1 diabetes

AIMS/HYPOTHESIS: Pancreatic beta cells are subjected to exogenous damaging factors such as proinflammatory cytokines or excess glucose that can cause accumulation of damage-inducing reactive oxygen species during the pathogenesis of diabetes. We and others have shown that beta cell autophagy can red...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Muralidharan, Charanya, Conteh, Abass M., Marasco, Michelle R., Crowder, Justin J., Kuipers, Jeroen, de Boer, Pascal, Linnemann, Amelia K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940272/
https://ncbi.nlm.nih.gov/pubmed/33515072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-021-05387-6
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