Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response

Production of reactive oxygen species (ROS) is a key instigator of β-cell dysfunction in diabetes. The pleiotropic cytokine interleukin 6 (IL-6) has previously been linked to β-cell autophagy but has not been studied in the context of β-cell antioxidant response. We used a combination of animal mode...

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Détails bibliographiques
Publié dans:Diabetes
Auteurs principaux: Marasco, Michelle R., Conteh, Abass M., Reissaus, Christopher A., Cupit, John E., Appleman, Evan M., Mirmira, Raghavendra G., Linnemann, Amelia K.
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2018
Sujets:
Islet Studies
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054440/
https://ncbi.nlm.nih.gov/pubmed/29784660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1280
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