An In Vivo Zebrafish Model for Interrogating ROS-Mediated Pancreatic β-Cell Injury, Response, and Prevention

It is well known that a chronic state of elevated reactive oxygen species (ROS) in pancreatic β-cells impairs their ability to release insulin in response to elevated plasma glucose. Moreover, at its extreme, unmitigated ROS drives regulated cell death. This dysfunctional state of ROS buildup can re...

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Библиографические подробности
Опубликовано в: :Oxid Med Cell Longev
Главные авторы: Kulkarni, Abhishek A., Conteh, Abass M., Sorrell, Cody A., Mirmira, Anjali, Tersey, Sarah A., Mirmira, Raghavendra G., Linnemann, Amelia K., Anderson, Ryan M.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896207/
https://ncbi.nlm.nih.gov/pubmed/29785241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1324739
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