An In Vivo Zebrafish Model for Interrogating ROS-Mediated Pancreatic β-Cell Injury, Response, and Prevention

It is well known that a chronic state of elevated reactive oxygen species (ROS) in pancreatic β-cells impairs their ability to release insulin in response to elevated plasma glucose. Moreover, at its extreme, unmitigated ROS drives regulated cell death. This dysfunctional state of ROS buildup can re...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Kulkarni, Abhishek A., Conteh, Abass M., Sorrell, Cody A., Mirmira, Anjali, Tersey, Sarah A., Mirmira, Raghavendra G., Linnemann, Amelia K., Anderson, Ryan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896207/
https://ncbi.nlm.nih.gov/pubmed/29785241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1324739
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