Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E(2) Signaling and Enhances Diabetic β-Cell Function

Prostaglandin E(2) (PGE(2)) is derived from arachidonic acid, whereas PGE(3) is derived from eicosapentaenoic acid (EPA) using the same downstream metabolic enzymes. Little is known about the impact of EPA and PGE(3) on β-cell function, particularly in the diabetic state. In this work, we determined...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Diabetes
Main Authors: Neuman, Joshua C., Schaid, Michael D., Brill, Allison L., Fenske, Rachel J., Kibbe, Carly R., Fontaine, Danielle A., Sdao, Sophia M., Brar, Harpreet K., Connors, Kelsey M., Wienkes, Haley N., Eliceiri, Kevin W., Merrins, Matthew J., Davis, Dawn B., Kimple, Michelle E.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2017
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440023/
https://ncbi.nlm.nih.gov/pubmed/28193789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-1362
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