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Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E(2) Signaling and Enhances Diabetic β-Cell Function

Prostaglandin E(2) (PGE(2)) is derived from arachidonic acid, whereas PGE(3) is derived from eicosapentaenoic acid (EPA) using the same downstream metabolic enzymes. Little is known about the impact of EPA and PGE(3) on β-cell function, particularly in the diabetic state. In this work, we determined...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Neuman, Joshua C., Schaid, Michael D., Brill, Allison L., Fenske, Rachel J., Kibbe, Carly R., Fontaine, Danielle A., Sdao, Sophia M., Brar, Harpreet K., Connors, Kelsey M., Wienkes, Haley N., Eliceiri, Kevin W., Merrins, Matthew J., Davis, Dawn B., Kimple, Michelle E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440023/
https://ncbi.nlm.nih.gov/pubmed/28193789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-1362
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