In The Blood: Connecting Variant to Function In Human Hematopoiesis

par Nandakumar, Satish K., Liao, Xiaotian, Sankaran, Vijay G.
Publié dans Trends Genet (2020)

Advances in Understanding Erythropoiesis: Evolving Perspectives

par Nandakumar, Satish K., Ulirsch, Jacob C., Sankaran, Vijay G.
Publié dans Br J Haematol (2016)

Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits

par Ulirsch, Jacob C., Nandakumar, Satish K., Wang, Li, Giani, Felix C., Zhang, Xiaolan, Rogov, Peter, Melnikov, Alexandre, McDonel, Patrick, Do, Ron, Mikkelsen, Tarjei S., Sankaran, Vijay G.
Publié dans Cell (2016)

Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis

par Ludwig, Leif S., Lareau, Caleb A., Bao, Erik L., Nandakumar, Satish K., Muus, Christoph, Ulirsch, Jacob C., Chowdhary, Kaitavjeet, Buenrostro, Jason D., Mohandas, Narla, An, Xiuli, Aryee, Martin J., Regev, Aviv, Sankaran, Vijay G.
Publié dans Cell Rep (2019)

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis

par Nandakumar, Satish K, McFarland, Sean K, Mateyka, Laura M, Lareau, Caleb A, Ulirsch, Jacob C, Ludwig, Leif S, Agarwal, Gaurav, Engreitz, Jesse M, Przychodzen, Bartlomiej, McConkey, Marie, Cowley, Glenn S, Doench, John G, Maciejewski, Jaroslaw P, Ebert, Benjamin L, Root, David E, Sankaran, Vijay G
Publié dans eLife (2019)

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

par Guo, Michael H., Nandakumar, Satish K., Ulirsch, Jacob C., Zekavat, Seyedeh M., Buenrostro, Jason D., Natarajan, Pradeep, Salem, Rany M., Chiarle, Roberto, Mitt, Mario, Kals, Mart, Pärn, Kalle, Fischer, Krista, Milani, Lili, Mägi, Reedik, Palta, Priit, Gabriel, Stacey B., Metspalu, Andres, Lander, Eric S., Kathiresan, Sekar, Hirschhorn, Joel N., Esko, Tõnu, Sankaran, Vijay G.
Publié dans Proc Natl Acad Sci U S A (2017)

Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction

par Verboon, Jeffrey M., Mahmut, Dilnar, Kim, Ah Ram, Nakamura, Mitsutoshi, Abdulhay, Nour J., Nandakumar, Satish K., Gupta, Namrata, Akie, Thomas E., Geddis, Amy E., Manes, Becky, Kapp, Meghan E., Hofmann, Inga, Gabriel, Stacey B., Klein, Daryl E., Williams, David A., Frangoul, Haydar A., Parkhurst, Susan M., Crane, Genevieve M., Cantor, Alan B., Sankaran, Vijay G.
Publié dans J Clin Immunol (2020)

Common variants in signaling transcription factor binding sites drive phenotypic variability in red blood cell traits

par Choudhuri, Avik, Trompouki, Eirini, Abraham, Brian J., Colli, Leandro M., Kock, Kian Hong, Mallard, William, Yang, Min–Lee, Vinjamur, Divya S., Ghamari, Alireza, Sporrij, Audrey, Hoi, Karen, Hummel, Barbara, Boatman, Sonja, Chan, Victoria, Tseng, Sierra, Nandakumar, Satish K., Yang, Song, Lichtig, Asher, Superdock, Michael, Grimes, Seraj N., Bowman, Teresa V., Zhou, Yi, Takahashi, Shinichiro, Joehanes, Roby, Cantor, Alan B., Bauer, Daniel E., Ganesh, Santhi K., Rinn, John, Albert, Paul S., Bulyk, Martha L., Chanock, Stephen J., Young, Richard A., Zon, Leonard I.
Publié dans Nat Genet (2020)

Inherited myeloproliferative neoplasm risk impacts hematopoietic stem cells

par Bao, Erik L., Nandakumar, Satish K., Liao, Xiaotian, Bick, Alexander G., Karjalainen, Juha, Tabaka, Marcin, Gan, Olga I., Havulinna, Aki, Kiiskinen, Tuomo, Lareau, Caleb A., de Lapuente Portilla, Aitzkoa Lopez, Li, Bo, Emdin, Connor, Codd, Veryan, Nelson, Christopher P., Walker, Christopher J., Churchhouse, Claire, de la Chapelle, Albert, Klein, Daryl E., Nilsson, Björn, Wilson, Peter W.F., Cho, Kelly, Pyarajan, Saiju, Gaziano, J. Michael, Samani, Nilesh J., Regev, Aviv, Palotie, Aarno, Neale, Benjamin M., Dick, John E., Natarajan, Pradeep, O’Donnell, Christopher J., Daly, Mark J., Milyavsky, Michael, Kathiresan, Sekar, Sankaran, Vijay G.
Publié dans Nature (2020)

Inherited Causes of Clonal Hematopoiesis in 97,691 TOPMed Whole Genomes

par Bick, Alexander G., Weinstock, Joshua S., Nandakumar, Satish K., Fulco, Charles P., Bao, Erik L., Zekavat, Seyedeh M., Szeto, Mindy D., Liao, Xiaotian, Leventhal, Matthew J., Nasser, Joseph, Chang, Kyle, Laurie, Cecelia, Burugula, Bala Bharathi, Gibson, Christopher J., Lin, Amy E., Taub, Margaret A., Aguet, Francois, Ardlie, Kristin, Mitchell, Braxton D., Barnes, Kathleen C., Moscati, Arden, Fornage, Myriam, Redline, Susan, Psaty, Bruce M., Silverman, Edwin K., Weiss, Scott T., Palmer, Nicholette D., Vasan, Ramachandran S., Burchard, Esteban G., Kardia, Sharon L. R., He, Jiang, Kaplan, Robert C., Smith, Nicholas L., Arnett, Donna K., Schwartz, David A., Correa, Adolfo, de Andrade, Mariza, Guo, Xiuqing, Konkle, Barbara A., Custer, Brian, Peralta, Juan M., Gui, Hongsheng, Meyers, Deborah A., McGarvey, Stephen T., Chen, Ida Yii-Der., Shoemaker, M. Benjamin, Peyser, Patricia A., Broome, Jai G., Gogarten, Stephanie M., Wang, Fei Fei, Wong, Quenna, Montasser, May E., Daya, Michelle, Kenny, Eimear E., North, Kari E., Launer, Lenore J., Cade, Brian E., Bis, Joshua C., Cho, Michael H., Lasky-Su, Jessica, Bowden, Donald W., Cupples, L. Adrienne., Mak, Angel C., Becker, Lewis C., Smith, Jennifer A., Kelly, Tanika N., Aslibekyan, Stella, Heckbert, Susan R., Tiwari, Hemant K., Yang, Ivana V., Heit, John A., Lubitz, Steven, Johnsen, Jill M., Curran, Joanne E., Wenzel, Sally E., Weeks, Daniel E., Rao, Dabeeru C., Darbar, Dawood, Moon, Jee-Young, Tracy, Russell P., Buth, Erin J., Rafaels, Nicholas, Loos, Ruth J.F., Durda, Peter, Liu, Yongmei, Hou, Lifang, Lee, Jiwon, Kachroo, Priyadarshini, Freedman, Barry I., Levy, Daniel, Bielak, Lawrence F., Hixson, James E., Floyd, James S., Whitsel, Eric A., Ellinor, Patrick T., Irvin, Marguerite R., Fingerlin, Tasha E., Raffield, Laura M., Armasu, Sebastian M., Wheeler, Marsha M., Sabino, Ester C., Blangero, John, Williams, L. Keoki, Levy, Bruce D., Huey-Herng Sheu, Wayne, Roden, Dan M., Boerwinkle, Eric, Manson, JoAnn E., Mathias, Rasika A., Desai, Pinkal, Taylor, Kent D., Johnson, Andrew D., Auer, Paul L., Kooperberg, Charles, Laurie, Cathy C., Blackwell, Thomas W., Smith, Albert V., Zhao, Hongyu, Lange, Ethan, Lange, Leslie, Rich, Stephen S., Rotter, Jerome I., Wilson, James G., Scheet, Paul, Kitzman, Jacob O., Lander, Eric S., Engreitz, Jesse M., Ebert, Benjamin L., Reiner, Alexander P., Jaiswal, Siddhartha, Abecasis, Gonçalo, Sankaran, Vijay G., Kathiresan, Sekar, Natarajan, Pradeep
Publié dans Nature (2020)