Chemistry of opioids

Por Nagase, Hiroshi.
Publicado em 2011

Synthesis and Pharmacology of a Novel κ Opioid Receptor (KOR) Agonist with a 1,3,5-Trioxazatriquinane Skeleton

Por Hirayama, Shigeto, Wada, Naohisa, Nemoto, Toru, Iwai, Takashi, Fujii, Hideaki, Nagase, Hiroshi
Publicado em 2014

PT706. Hypothalamic opioid receptors control feeding behavior though orexin and GABA Neurons

Por Ikeda, Hiroko, Ardianto, Chrismawan, Yonemochi, Naomi, Yamamoto, Shogo, Yang, Lizhe, Takenoya, Fumiko, Shioda, Seiji, Nagase, Hiroshi, Kamei, Junzo
Publicado no Int J Neuropsychopharmacol (2016)

Identification of the G-protein-coupled ORL1 receptor in the mouse spinal cord by [(35)S]-GTPγS binding and immunohistochemistry

Por Narita, Minoru, Mizoguchi, Hirokazu, Oji, David E, Narita, Michiko, Dun, Nae J, Hwang, Bang H, Nagase, Hiroshi, Tseng, Leon F
Publicado em 1999

к Opioids inhibit tumor angiogenesis by suppressing VEGF signaling

Por Yamamizu, Kohei, Furuta, Sadayoshi, Hamada, Yusuke, Yamashita, Akira, Kuzumaki, Naoko, Narita, Michiko, Doi, Kento, Katayama, Shiori, Nagase, Hiroshi, Yamashita, Jun K., Narita, Minoru
Publicado em 2013

Novel Delta Opioid Receptor Agonists with Oxazatricyclodecane Structure

Por Fujii, Hideaki, Hayashida, Kohei, Saitoh, Akiyoshi, Yokoyama, Akinobu, Hirayama, Shigeto, Iwai, Takashi, Nakata, Eriko, Nemoto, Toru, Sudo, Yuka, Uezono, Yasuhito, Yamada, Mitsuhiko, Nagase, Hiroshi
Publicado em 2014

Expression levels of brown/beige adipocyte-related genes in fat depots of vitamin A-restricted fattening cattle

Por Chen, Hsuan-Ju, Ihara, Tsubasa, Yoshioka, Hidetugu, Itoyama, Erina, Kitamura, Shoko, Nagase, Hiroshi, Murakami, Hiroaki, Hoshino, Yoichiro, Murakami, Masaru, Tomonaga, Shozo, Matsui, Tohru, Funaba, Masayuki
Publicado no J Anim Sci (2018)

In silico design of novel probes for the atypical opioid receptor MRGPRX2

Por Lansu, Katherine, Karpiak, Joel, Liu, Jing, Huang, Xi-Ping, McCorvy, John D., Kroeze, Wesley K., Che, Tao, Nagase, Hiroshi, Carroll, Frank I., Jin, Jian, Shoichet, Brian K., Roth, Bryan L.
Publicado no Nat Chem Biol (2017)

Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models

Por Irukayama-Tomobe, Yoko, Ogawa, Yasuhiro, Tominaga, Hiromu, Ishikawa, Yukiko, Hosokawa, Naoto, Ambai, Shinobu, Kawabe, Yuki, Uchida, Shuntaro, Nakajima, Ryo, Saitoh, Tsuyoshi, Kanda, Takeshi, Vogt, Kaspar, Sakurai, Takeshi, Nagase, Hiroshi, Yanagisawa, Masashi
Publicado no Proc Natl Acad Sci U S A (2017)

Peripheral Opioid Antagonist Enhances the Effect of Anti-Tumor Drug by Blocking a Cell Growth-Suppressive Pathway In Vivo

Por Suzuki, Masami, Chiwaki, Fumiko, Sawada, Yumi, Ashikawa, Maho, Aoyagi, Kazuhiko, Fujita, Takeshi, Yanagihara, Kazuyoshi, Komatsu, Masayuki, Narita, Minoru, Suzuki, Tsutomu, Nagase, Hiroshi, Kushima, Ryoji, Sakamoto, Hiromi, Fukagawa, Takeo, Katai, Hitoshi, Nakagama, Hitoshi, Yoshida, Teruhiko, Uezono, Yasuhito, Sasaki, Hiroki
Publicado no PLoS One (2015)

Dynorphin Acts as a Neuromodulator to Inhibit Itch in the Dorsal Horn of the Spinal Cord

Por Kardon, Adam P., Polgár, Erika, Hachisuka, Junichi, Snyder, Lindsey M., Cameron, Darren, Savage, Sinead, Cai, Xiaoyun, Karnup, Sergei, Fan, Christopher R., Hemenway, Gregory M., Bernard, Carcha S., Schwartz, Erica S., Nagase, Hiroshi, Schwarzer, Christoph, Watanabe, Masahiko, Furuta, Takahiro, Kaneko, Takeshi, Koerber, H. Richard, Todd, Andrew J., Ross, Sarah E.
Publicado em 2014

Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors

Por Wang, Yibing, Cao, Liqin, Lee, Chia-Ying, Matsuo, Tomohiko, Wu, Kejia, Asher, Greg, Tang, Lijun, Saitoh, Tsuyoshi, Russell, Jamie, Klewe-Nebenius, Daniela, Wang, Li, Soya, Shingo, Hasegawa, Emi, Chérasse, Yoan, Zhou, Jiamin, Li, Yuwenbin, Wang, Tao, Zhan, Xiaowei, Miyoshi, Chika, Irukayama, Yoko, Cao, Jie, Meeks, Julian P., Gautron, Laurent, Wang, Zhiqiang, Sakurai, Katsuyasu, Funato, Hiromasa, Sakurai, Takeshi, Yanagisawa, Masashi, Nagase, Hiroshi, Kobayakawa, Reiko, Kobayakawa, Ko, Beutler, Bruce, Liu, Qinghua
Publicado no Nat Commun (2018)