Genome-Wide Modulation of Gene Transcription in Ovarian Carcinoma Cells by a New Mithramycin Analogue

av Vizcaíno, Carolina, Núñez, Luz-Elena, Morís, Francisco, Portugal, José
Publicerad 2014

Involvement of the Beta Subunit of RNA Polymerase in Resistance to Streptolydigin and Streptovaricin in the Producer Organisms Streptomyces lydicus and Streptomyces spectabilis

av Sánchez-Hidalgo, Marina, Núñez, Luz Elena, Méndez, Carmen, Salas, José A.
Publicerad 2010

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2

av Pandiella, Atanasio, Morís, Francisco, Ocaña, Alberto, Núñez, Luz-Elena, Montero, Juan C.
I publikationen Oncotarget (2015)

Mutational Analysis of the Thienamycin Biosynthetic Gene Cluster from Streptomyces cattleya

av Rodríguez, Miriam, Núñez, Luz Elena, Braña, Alfredo F., Méndez, Carmen, Salas, José A., Blanco, Gloria
Publicerad 2011

Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma

av Federico, Aniello, Steinfass, Tamara, Larribère, Lionel, Novak, Daniel, Morís, Francisco, Núñez, Luz-Elena, Umansky, Viktor, Utikal, Jochen
I publikationen Mol Ther Oncolytics (2020)

Modulation of the Activity of Sp Transcription Factors by Mithramycin Analogues as a New Strategy for Treatment of Metastatic Prostate Cancer

av Malek, Anastasia, Núñez, Luz-Elena, Magistri, Marco, Brambilla, Lara, Jovic, Sandra, Carbone, Giuseppina M., Morís, Francisco, Catapano, Carlo V.
Publicerad 2012

The chromomycin CmmA acetyltransferase: a membrane‐bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin

av García, Beatriz, González‐Sabín, Javier, Menéndez, Nuria, Braña, Alfredo F., Núñez, Luz Elena, Morís, Francisco, Salas, José A., Méndez, Carmen
Publicerad 2011

Pleiotropic Anti-Angiogenic and Anti-Oncogenic Activities of the Novel Mithralog Demycarosyl-3D-ß-D-Digitoxosyl-Mithramycin SK (EC-8042)

av Fernández-Guizán, Azahara, López-Soto, Alejandro, Acebes-Huerta, Andrea, Huergo-Zapico, Leticia, Villa-Álvarez, Mónica, Núñez, Luz-Elena, Morís, Francisco, Gonzalez, Segundo
I publikationen PLoS One (2015)

Phospho-kinase profile of colorectal tumors guides in the selection of multi-kinase inhibitors

av Serrano-Heras, Gemma, Cuenca-López, María Dolores, Montero, Juan Carlos, Corrales-Sanchez, Verónica, Morales, Jorge Carlos, Núñez, Luz-Elena, Morís, Francisco, Pandiella, Atanasio, Ocaña, Alberto
I publikationen Oncotarget (2015)

Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma

av Tornin, Juan, Martinez-Cruzado, Lucia, Santos, Laura, Rodriguez, Aida, Núñez, Luz-Elena, Oro, Patricia, Hermosilla, Maria Ana, Allonca, Eva, Fernández-García, Maria Teresa, Astudillo, Aurora, Suarez, Carlos, Morís, Francisco, Rodriguez, Rene
I publikationen Oncotarget (2016)

High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies

av Buchmann, Anina, Eitel, Michael, Koch, Pierre, Schwarz, Paul N., Stegmann, Evi, Wohlleben, Wolfgang, Wolański, Marcin, Krawiec, Michał, Zakrzewska-Czerwińska, Jolanta, Méndez, Carmen, Botas, Alma, Núñez, Luz Elena, Morís, Francisco, Cortés, Jesus, Gross, Harald
I publikationen Genome Announc (2016)

A novel LysR‐type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin

av Wolański, Marcin, Krawiec, Michał, Schwarz, Paul N., Stegmann, Evi, Wohlleben, Wolfgang, Buchmann, Anina, Gross, Harald, Eitel, Michael, Koch, Pierre, Botas, Alma, Méndez, Carmen, Núñez, Luz Elena, Morís, Francisco, Cortés, Jesus, Zakrzewska‐Czerwińska, Jolanta
I publikationen Eng Life Sci (2020)

The Mithralog EC-7072 Induces Chronic Lymphocytic Leukemia Cell Death by Targeting Tonic B-Cell Receptor Signaling

av Lorenzo-Herrero, Seila, Sordo-Bahamonde, Christian, Bretones, Gabriel, Payer, Ángel R., González-Rodríguez, Ana P., González-García, Esther, Pérez-Escuredo, Jhudit, Villa-Álvarez, Mónica, Núñez, Luz-Elena, Morís, Francisco, Gonzalez, Segundo, López-Soto, Alejandro
I publikationen Front Immunol (2019)

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer

av Cuenca-López, María Dolores, Serrano-Heras, Gemma, Montero, Juan Carlos, Corrales-Sánchez, Verónica, Gomez-Juarez, Mónica, Gascón-Escribano, Maria José, Carlos Morales, Jorge, Voisin, Veronique, Núñez, Luz Elena, Morís, Francisco, Bader, Gary D., Pandiella, Atanasio, Ocaña, Alberto
I publikationen Oncotarget (2015)

Genetic Engineering in Combination with Semi‐Synthesis Leads to a New Route for Gram‐Scale Production of the Immunosuppressive Natural Product Brasilicardin A

av Botas, Alma, Eitel, Michael, Schwarz, Paul N., Buchmann, Anina, Costales, Paula, Núñez, Luz Elena, Cortés, Jesús, Morís, Francisco, Krawiec, Michał, Wolański, Marcin, Gust, Bertolt, Rodriguez, Mirna, Fischer, Wolf‐Nicolas, Jandeleit, Bernd, Zakrzewska‐Czerwińska, Jolanta, Wohlleben, Wolfgang, Stegmann, Evi, Koch, Pierre, Méndez, Carmen, Gross, Harald
I publikationen Angew Chem Int Ed Engl (2021)

Identification of mithramycin analogs with improved targeting of the EWS-FLI1 transcription factor

av Osgood, Christy L, Maloney, Nichole, Kidd, Christopher G, Kitchen-Goosen, Susan, Segars, Laura, Gebregiorgis, Meti, Woldemichael, Girma M, He, Min, Sankar, Savita, Lessnick, Steve, Kang, Min, Smith, Malcolm, Turner, Lisa, Madaj, Zachary B., Winn, Mary E., Núñez, Luz-Elena, González-Sabín, Javier, Helman, Lee J, Morís, Francisco, Grohar, Patrick J
I publikationen Clin Cancer Res (2016)