Genetic Engineering in Combination with Semi‐Synthesis Leads to a New Route for Gram‐Scale Production of the Immunosuppressive Natural Product Brasilicardin A

Brasilicardin A (1) consists of an unusual anti/syn/anti‐perhydrophenanthrene skeleton with a carbohydrate side chain and an amino acid moiety. It exhibits potent immunosuppressive activity, yet its mode of action differs from standard drugs that are currently in use. Further pre‐clinical evaluation...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Botas, Alma, Eitel, Michael, Schwarz, Paul N., Buchmann, Anina, Costales, Paula, Núñez, Luz Elena, Cortés, Jesús, Morís, Francisco, Krawiec, Michał, Wolański, Marcin, Gust, Bertolt, Rodriguez, Mirna, Fischer, Wolf‐Nicolas, Jandeleit, Bernd, Zakrzewska‐Czerwińska, Jolanta, Wohlleben, Wolfgang, Stegmann, Evi, Koch, Pierre, Méndez, Carmen, Gross, Harald
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251711/
https://ncbi.nlm.nih.gov/pubmed/33768597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202015852
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars