HPF1 and nucleosomes mediate a dramatic switch in activity of PARP1 from polymerase to hydrolase

di Rudolph, Johannes, Roberts, Genevieve, Muthurajan, Uma M, Luger, Karolin
Pubblicato in eLife (2021)

Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes

di Clark, Nicholas J., Kramer, Michael, Muthurajan, Uma M., Luger, Karolin
Pubblicazione 2012

Analytical Ultracentrifugation (AUC): An Overview of the Application of Fluorescence and Absorbance AUC to the Study of Biological Macromolecules

di Edwards, Garrett B., Muthurajan, Uma M., Bowerman, Samuel, Luger, Karolin
Pubblicato in Curr Protoc Mol Biol (2020)

Solution structure(s) of trinucleosomes from contrast variation SAXS

di Mauney, Alexander W, Muthurajan, Uma M, Luger, Karolin, Pollack, Lois
Pubblicato in Nucleic Acids Res (2021)

Histone Chaperone FACT Coordinates Nucleosome Interaction through Multiple Synergistic Binding Events

di Winkler, Duane D., Muthurajan, Uma M., Hieb, Aaron R., Luger, Karolin
Pubblicazione 2011

Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA

di Sekiya, Takashi, Muthurajan, Uma M., Luger, Karolin, Tulin, Alexei V., Zaret, Kenneth S.
Pubblicazione 2009

The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays

di Muthurajan, Uma M., McBryant, Steven J., Lu, Xu, Hansen, Jeffrey C., Luger, Karolin
Pubblicazione 2011

Biophysical analysis and small-angle X-ray scattering-derived structures of MeCP2–nucleosome complexes

di Yang, Chenghua, van der Woerd, Mark J., Muthurajan, Uma M., Hansen, Jeffrey C., Luger, Karolin
Pubblicazione 2011

The role of the nucleosome acidic patch in modulating higher order chromatin structure

di Kalashnikova, Anna A., Porter-Goff, Mary E., Muthurajan, Uma M., Luger, Karolin, Hansen, Jeffrey C.
Pubblicazione 2013

Crystal structures of histone Sin mutant nucleosomes reveal altered protein–DNA interactions

di Muthurajan, Uma M, Bao, Yunhe, Forsberg, Lawrence J, Edayathumangalam, Rajeswari S, Dyer, Pamela N, White, Cindy L, Luger, Karolin
Pubblicazione 2004

Assembly of Nucleosomal Arrays from Recombinant Core Histones and Nucleosome Positioning DNA

di Rogge, Ryan A., Kalashnikova, Anna A., Muthurajan, Uma M., Porter-Goff, Mary E., Luger, Karolin, Hansen, Jeffrey C.
Pubblicazione 2013

Biochemical and biophysical methods for analysis of Poly (ADP-Ribose) Polymerase 1 and its interactions with chromatin

di Chassé, Maggie H, Muthurajan, Uma M, Clark, Nicholas J, Kramer, Michael A, Chakravarthy, Srinivas, Irving, Thomas, Luger, Karolin
Pubblicato in Methods Mol Biol (2017)

Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone

di Muthurajan, Uma M., Hepler, Maggie R. D., Hieb, Aaron R., Clark, Nicholas J., Kramer, Michael, Yao, Tingting, Luger, Karolin
Pubblicazione 2014

Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1

di Gaullier, Guillaume, Roberts, Genevieve, Muthurajan, Uma M., Bowerman, Samuel, Rudolph, Johannes, Mahadevan, Jyothi, Jha, Asmita, Rae, Purushka S., Luger, Karolin
Pubblicato in PLoS One (2020)

The transcription factor Spn1 regulates gene expression via a highly conserved novel structural motif

di Pujari, Venugopal, Radebaugh, Catherine A., Chodaparambil, Jayanth V., Muthurajan, Uma M., Almeida, Adam R., Fischbeck, Julie A., Luger, Karolin, Stargell, Laurie A.
Pubblicazione 2010

Molecular functions of the TLE tetramerization domain in Wnt target gene repression

di Chodaparambil, Jayanth V, Pate, Kira T, Hepler, Margretta R D, Tsai, Becky P, Muthurajan, Uma M, Luger, Karolin, Waterman, Marian L, Weis, William I
Pubblicazione 2014

Single and double box HMGB proteins differentially destabilize nucleosomes

di McCauley, Micah J, Huo, Ran, Becker, Nicole, Holte, Molly Nelson, Muthurajan, Uma M, Rouzina, Ioulia, Luger, Karolin, Maher, L James, Israeloff, Nathan E, Williams, Mark C
Pubblicato in Nucleic Acids Res (2019)

The Histone Variant H2A.W Defines Heterochromatin and Promotes Chromatin Condensation in Arabidopsis

di Yelagandula, Ramesh, Stroud, Hume, Holec, Sarah, Zhou, Keda, Feng, Suhua, Zhong, Xuehua, Muthurajan, Uma M., Nie, Xin, Kawashima, Tomokazu, Groth, Martin, Luger, Karolin, Jacobsen, Steven E., Berger, Frédéric
Pubblicato in Cell (2014)

Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation

di Klein, Brianna J., Muthurajan, Uma M., Lalonde, Marie-Eve, Gibson, Matthew D., Andrews, Forest H., Hepler, Maggie, Machida, Shinichi, Yan, Kezhi, Kurumizaka, Hitoshi, Poirier, Michael G., Côté, Jacques, Luger, Karolin, Kutateladze, Tatiana G.
Pubblicato in Nucleic Acids Res (2016)