Ubiquilin overexpression reduces GFP-polyalanine-induced protein aggregates and toxicity

Por Wang, Hongmin, Monteiro, Mervyn J.
Publicado em 2007

Ubiquilin interacts and enhances the degradation of expanded-polyglutamine proteins

Por Wang, Hongmin, Monteiro, Mervyn J.
Publicado em 2007

Increased Apoptosis Arising from Increased Expression of the Alzheimer's Disease–associated Presenilin-2 Mutation (N141I)

Por Janicki, Susan, Monteiro, Mervyn J.
Publicado em 1997

Ubiquilin at a crossroads in protein degradation pathways

Por Rothenberg, Cara, Monteiro, Mervyn J
Publicado em 2010

Defective Proteasome Delivery of Polyubiquitinated Proteins by Ubiquilin-2 Proteins Containing ALS Mutations

Por Chang, Lydia, Monteiro, Mervyn J.
Publicado no PLoS One (2015)

Dimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilins

Por Ford, Diana L., Monteiro, Mervyn J.
Publicado em 2006

Presenilin Overexpression Arrests Cells in the G1 Phase of the Cell Cycle : Arrest Potentiated by the Alzheimer’s Disease PS2(N141I) Mutant

Por Janicki, Susan M., Monteiro, Mervyn J.
Publicado em 1999

Studies of the role of ubiquitination in the interaction of ubiquilin with the loop and carboxyl terminal regions of presenilin-2

Por Ford, Diana L., Monteiro, Mervyn J.
Publicado em 2007

Ubiquilin regulates presenilin endoproteolysis and modulates γ-secretase components, Pen-2 and nicastrin

Por Massey, Leann K., Mah, Alex L., Monteiro, Mervyn J.
Publicado em 2005

Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death

Por Ugolino, Janet, Fang, Shengyun, Kubisch, Christian, Monteiro, Mervyn J.
Publicado em 2011

Effects of overexpression of Huntingtin proteins on mitochondrial integrity

Por Wang, Hongmin, Lim, Precious J., Karbowski, Mariusz, Monteiro, Mervyn J.
Publicado em 2009

Signature changes in ubiquilin expression in the R6/2 mouse model of Huntington’s disease

Por Safren, Nathaniel, Chang, Lydia, Dziki, Kristina M., Monteiro, Mervyn J.
Publicado no Brain Res (2014)

Identification of Ubiquilin, a Novel Presenilin Interactor That Increases Presenilin Protein Accumulation

Por Mah, Alex L., Perry, George, Smith, Mark A., Monteiro, Mervyn J.
Publicado em 2000

The role of cell cycle-mediated events in Alzheimer's disease

Por Raina, Arun K, Monteiro, Mervyn J, Mcshea, Andrew, Smith, Mark A
Publicado em 1999

A Myristoylated Calcium-binding Protein that Preferentially Interacts with the Alzheimer's Disease Presenilin 2 Protein

Por Stabler, Stacy M., Ostrowski, Lisa L., Janicki, Susan M., Monteiro, Mervyn J.
Publicado em 1999

Huntingtin Interacts with the Cue Domain of gp78 and Inhibits gp78 Binding to Ubiquitin and p97/VCP

Por Yang, Hui, Liu, Chao, Zhong, Yongwang, Luo, Shouqing, Monteiro, Mervyn J., Fang, Shengyun
Publicado em 2010

Importin β Interacts with the Endoplasmic Reticulum-associated Degradation Machinery and Promotes Ubiquitination and Degradation of Mutant α1-Antitrypsin

Por Zhong, Yongwang, Wang, Yang, Yang, Hui, Ballar, Petek, Lee, Jin-gu, Ye, Yihong, Monteiro, Mervyn J., Fang, Shengyun
Publicado em 2011

Cross-seeding of prions by aggregated α-synuclein leads to transmissible spongiform encephalopathy

Por Katorcha, Elizaveta, Makarava, Natallia, Lee, Young Jin, Lindberg, Iris, Monteiro, Mervyn J., Kovacs, Gabor G., Baskakov, Ilia V.
Publicado no PLoS Pathog (2017)

Kaposi's Sarcoma-Associated Herpesvirus K7 Protein Targets a Ubiquitin-Like/Ubiquitin-Associated Domain-Containing Protein To Promote Protein Degradation

Por Feng, Pinghui, Scott, Christopher W., Cho, Nam-Hyuk, Nakamura, Hiroyuki, Chung, Young-Hwa, Monteiro, Mervyn J., Jung, Jae U.
Publicado em 2004

Ubiquilin-1 Overexpression Increases the Lifespan and Delays Accumulation of Huntingtin Aggregates in the R6/2 Mouse Model of Huntington's Disease

Por Safren, Nathaniel, El Ayadi, Amina, Chang, Lydia, Terrillion, Chantelle E., Gould, Todd D., Boehning, Darren F., Monteiro, Mervyn J.
Publicado em 2014