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Identification of Ubiquilin, a Novel Presenilin Interactor That Increases Presenilin Protein Accumulation
Mutations in the highly homologous presenilin genes encoding presenilin-1 and presenilin-2 (PS1 and PS2) are linked to early-onset Alzheimer's disease (AD). However, apart from a role in early development, neither the normal function of the presenilins nor the mechanisms by which mutant protein...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2000
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169435/ https://ncbi.nlm.nih.gov/pubmed/11076969 |
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