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Identification of Ubiquilin, a Novel Presenilin Interactor That Increases Presenilin Protein Accumulation

Mutations in the highly homologous presenilin genes encoding presenilin-1 and presenilin-2 (PS1 and PS2) are linked to early-onset Alzheimer's disease (AD). However, apart from a role in early development, neither the normal function of the presenilins nor the mechanisms by which mutant protein...

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Detalhes bibliográficos
Main Authors: Mah, Alex L., Perry, George, Smith, Mark A., Monteiro, Mervyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169435/
https://ncbi.nlm.nih.gov/pubmed/11076969
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