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Signature changes in ubiquilin expression in the R6/2 mouse model of Huntington’s disease
Ubiquilin proteins have been implicated in the cause and the pathology of neurodegenerative diseases. In the R6/2 mouse model of Huntington’s disease (HD), ubiquilin levels decline during disease progression. Restoration of their levels by transgenic expression of ubiquilin-1 extends survival. Here...
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| Publicado no: | Brain Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4340744/ https://ncbi.nlm.nih.gov/pubmed/25511991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.12.008 |
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