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Cardiac dysfunction in the R6/2 mouse model of Huntington’s disease

Recent evidence suggests that mutant huntingtin protein-induced energetic perturbations contribute to neuronal dysfunction in Huntington’s disease (HD). Given the ubiquitous expression of huntingtin, other cell types with high energetic burden may be at risk for HD-related dysfunction. Early-onset c...

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Detalhes bibliográficos
Main Authors: Mihm, Michael J., Amann, Deborah M., Schanbacher, Brandon L., Altschuld, Ruth A., Bauer, John Anthony, Hoyt, Kari R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850107/
https://ncbi.nlm.nih.gov/pubmed/17126554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2006.09.016
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