Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases

by Cascão, Rita, Fonseca, João E., Moita, Luis F.
Published in Front Med (Lausanne) (2017)

The Cadherin Superfamily in Anopheles gambiae: a Comparative Study With Drosophila melanogaster

by Moita, Catarina, Simões, Sérgio, Moita, Luís F., Jacinto, António, Fernandes, Pedro
Published 2005

Drugs that simultaneously down-regulate IL-1β and TNF secretion significantly reduce inflammation in a rat model of antigen-induced arthritis

by Cascão, Rita, Vidal, Bruno, Raquel, Helena, Gupta, Vineet, Fonseca, João E, Moita, Luis F
Published 2011

Reverse genetics in the mosquito Anopheles gambiae: targeted disruption of the Defensin gene

by Blandin, Stéphanie, Moita, Luis F., Köcher, Thomas, Wilm, Matthias, Kafatos, Fotis C., Levashina, Elena A.
Published 2002

Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats

by Cascão, Rita, Vidal, Bruno, Lopes, Inês P., Paisana, Eunice, Rino, José, Moita, Luis F., Fonseca, João E.
Published in PLoS One (2015)

Endosomal MR1 Trafficking Plays a Key Role in Presentation of Mycobacterium tuberculosis Ligands to MAIT Cells

by Harriff, Melanie J., Karamooz, Elham, Burr, Ansen, Grant, Wilmon F., Canfield, Elizabeth T., Sorensen, Michelle L., Moita, Luis F., Lewinsohn, David M.
Published in PLoS Pathog (2016)

A Th2 Cytokine Profile in Appendicular Lavage Fluid Suggests Allergy as a Possible Etiology for Acute Appendicitis

by Carvalho, Nuno, Barros, André, Coelho, Hélder O., Moita, Catarina F., Neves-Costa, Ana, Pedroso, Dora, Borges, Filipe C., Moita, Luís F., Costa, Paulo M.
Published in Mediators Inflamm (2019)

Highly Dynamic Host Actin Reorganization around Developing Plasmodium Inside Hepatocytes

by Gomes-Santos, Carina S. S., Itoe, Maurice A., Afonso, Cristina, Henriques, Ricardo, Gardner, Rui, Sepúlveda, Nuno, Simões, Pedro D., Raquel, Helena, Almeida, António Paulo, Moita, Luis F., Frischknecht, Friedrich, Mota, Maria M.
Published 2012

An shRNA-Based Screen of Splicing Regulators Identifies SFRS3 as a Negative Regulator of IL-1β Secretion

by Moura-Alves, Pedro, Neves-Costa, Ana, Raquel, Helena, Pacheco, Teresa Raquel, D'Almeida, Bruno, Rodrigues, Raquel, Cadima-Couto, Iris, Chora, Ângelo, Oliveira, Mariana, Gama-Carvalho, Margarida, Hacohen, Nir, Moita, Luis F.
Published 2011

SAMHD1-dependent retroviral control and escape in mice

by Rehwinkel, Jan, Maelfait, Jonathan, Bridgeman, Anne, Rigby, Rachel, Hayward, Bruce, Liberatore, Rachel A, Bieniasz, Paul D, Towers, Greg J, Moita, Luis F, Crow, Yanick J, Bonthron, David T, Reis e Sousa, Caetano
Published 2013

CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis

by Santos, Isa, Colaço, Henrique G., Neves-Costa, Ana, Seixas, Elsa, Velho, Tiago R., Pedroso, Dora, Barros, André, Martins, Rui, Carvalho, Nuno, Payen, Didier, Weis, Sebastian, Yi, Hyon-Seung, Shong, Minho, Moita, Luís F.
Published in Proc Natl Acad Sci U S A (2020)

Tetracycline Antibiotics Induce Host-Dependent Disease Tolerance to Infection

by Colaço, Henrique G., Barros, André, Neves-Costa, Ana, Seixas, Elsa, Pedroso, Dora, Velho, Tiago, Willmann, Katharina L., Faisca, Pedro, Grabmann, Gerlinde, Yi, Hyon-Seung, Shong, Minho, Benes, Vladimir, Weis, Sebastian, Köcher, Thomas, Moita, Luís F.
Published in Immunity (2021)

Synaptotagmin-mediated vesicle fusion regulates cell migration

by Colvin, Richard A, Means, Terry K, Diefenbach, Thomas J, Moita, Luis F, Friday, Robert P, Sever, Sanja, Campanella, Gabriele S V, Abrazinski, Tabitha, Manice, Lindsay A, Moita, Catarina, Andrews, Norma W, Wu, Dianqing, Hacohen, Nir, Luster, Andrew D
Published 2010

Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis

by Almeida, Luís, Dhillon-LaBrooy, Ayesha, Castro, Carla N., Adossa, Nigatu, Carriche, Guilhermina M., Guderian, Melanie, Lippens, Saskia, Dennerlein, Sven, Hesse, Christina, Lambrecht, Bart N., Berod, Luciana, Schauser, Leif, Blazar, Bruce R., Kalesse, Markus, Müller, Rolf, Moita, Luís F., Sparwasser, Tim
Published in Immunity (2021)

Small Molecule–Mediated Activation of the Integrin CD11b/CD18 Reduces Inflammatory Disease

by Maiguel, Dony, Faridi, Mohd Hafeez, Wei, Changli, Kuwano, Yoshihiro, Balla, Keir M., Hernandez, Dayami, Barth, Constantinos J., Lugo, Geanncarlo, Donnelly, Mary, Nayer, Ali, Moita, Luis F., Schürer, Stephan, Traver, David, Ruiz, Phillip, Vazquez-Padron, Roberto I., Ley, Klaus, Reiser, Jochen, Gupta, Vineet
Published in Sci Signal (2011)

Dendritic Cells Control Fibroblastic Reticular Network Tension and Lymph Node Expansion

by Acton, Sophie E., Farrugia, Aaron J., Astarita, Jillian L., Mourão-Sá, Diego, Jenkins, Robert P., Nye, Emma, Hooper, Steven, van Blijswijk, Janneke, Rogers, Neil C., Snelgrove, Kathryn J., Rosewell, Ian, Moita, Luis F., Stamp, Gordon, Turley, Shannon J., Sahai, Erik, Sousa, Caetano Reis e
Published in Nature (2014)

Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis

by Badenes, Marina, Amin, Abdulbasit, González-García, Ismael, Félix, Inês, Burbridge, Emma, Cavadas, Miguel, Ortega, Francisco José, de Carvalho, Érika, Faísca, Pedro, Carobbio, Stefania, Seixas, Elsa, Pedroso, Dora, Neves-Costa, Ana, Moita, Luís F., Fernández-Real, José Manuel, Vidal-Puig, António, Domingos, Ana, López, Miguel, Adrain, Colin
Published in Mol Metab (2019)

Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1

by Lee, Ha Won, Khan, Samia Q., Khaliqdina, Shehryar, Altintas, Mehmet M., Grahammer, Florian, Zhao, Jimmy L., Koh, Kwi Hye, Tardi, Nicholas J., Faridi, Mohd. Hafeez, Geraghty, Terese, Cimbaluk, David J., Susztak, Katalin, Moita, Luis F., Baltimore, David, Tharaux, Pierre-Louis, Huber, Tobias B., Kretzler, Matthias, Bitzer, Markus, Reiser, Jochen, Gupta, Vineet
Published in J Biol Chem (2017)

Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis

by Figueiredo, Nuno, Chora, Angelo, Raquel, Helena, Pejanovic, Nadja, Pereira, Pedro, Hartleben, Björn, Neves-Costa, Ana, Moita, Catarina, Pedroso, Dora, Pinto, Andreia, Marques, Sofia, Faridi, Hafeez, Costa, Paulo, Gozzelino, Raffaella, Zhao, Jimmy L., Soares, Miguel P., Gama-Carvalho, Margarida, Martinez, Jennifer, Zhang, Qingshuo, Döring, Gerd, Grompe, Markus, Simas, J. Pedro, Huber, Tobias B., Baltimore, David, Gupta, Vineet, Green, Douglas R., Ferreira, João A., Moita, Luis F.
Published 2013

Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15

by Cimino, Irene, Kim, Hanna, Tung, Y. C. Loraine, Pedersen, Kent, Rimmington, Debra, Tadross, John A., Kohnke, Sara N., Neves-Costa, Ana, Barros, André, Joaquim, Stephanie, Bennett, Don, Melvin, Audrey, Lockhart, Samuel M., Rostron, Anthony J., Scott, Jonathan, Liu, Hui, Burling, Keith, Barker, Peter, Clatworthy, Menna R., Lee, E-Chiang, Simpson, A. John, Yeo, Giles S. H., Moita, Luís F., Bence, Kendra K., Jørgensen, Sebastian Beck, Coll, Anthony P., Breen, Danna M., O’Rahilly, Stephen
Published in Proc Natl Acad Sci U S A (2021)