Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis

Severe sepsis remains a poorly understood systemic inflammatory condition with high mortality rates and limited therapeutic options in addition to organ support measures. Here we show that the clinically approved group of anthracyclines acts therapeutically at a low dose regimen to confer robust pro...

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Bibliografiska uppgifter
Huvudupphovsmän: Figueiredo, Nuno, Chora, Angelo, Raquel, Helena, Pejanovic, Nadja, Pereira, Pedro, Hartleben, Björn, Neves-Costa, Ana, Moita, Catarina, Pedroso, Dora, Pinto, Andreia, Marques, Sofia, Faridi, Hafeez, Costa, Paulo, Gozzelino, Raffaella, Zhao, Jimmy L., Soares, Miguel P., Gama-Carvalho, Margarida, Martinez, Jennifer, Zhang, Qingshuo, Döring, Gerd, Grompe, Markus, Simas, J. Pedro, Huber, Tobias B., Baltimore, David, Gupta, Vineet, Green, Douglas R., Ferreira, João A., Moita, Luis F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968948/
https://ncbi.nlm.nih.gov/pubmed/24184056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.08.039
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