Dendritic Cells Control Fibroblastic Reticular Network Tension and Lymph Node Expansion

Following immunogenic challenge, infiltrating and dividing lymphocytes significantly increase lymph node (LN) cellularity leading to organ expansion(1,2). Here we report that the physical elasticity of LNs is maintained in part by podoplanin (PDPN) signalling in stromal fibroblastic reticular cells...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Acton, Sophie E., Farrugia, Aaron J., Astarita, Jillian L., Mourão-Sá, Diego, Jenkins, Robert P., Nye, Emma, Hooper, Steven, van Blijswijk, Janneke, Rogers, Neil C., Snelgrove, Kathryn J., Rosewell, Ian, Moita, Luis F., Stamp, Gordon, Turley, Shannon J., Sahai, Erik, Sousa, Caetano Reis e
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235005/
https://ncbi.nlm.nih.gov/pubmed/25341788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13814
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