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Dendritic Cells Control Fibroblastic Reticular Network Tension and Lymph Node Expansion
Following immunogenic challenge, infiltrating and dividing lymphocytes significantly increase lymph node (LN) cellularity leading to organ expansion(1,2). Here we report that the physical elasticity of LNs is maintained in part by podoplanin (PDPN) signalling in stromal fibroblastic reticular cells...
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| 出版年: | Nature |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4235005/ https://ncbi.nlm.nih.gov/pubmed/25341788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13814 |
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