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Altered lymph node composition in diphtheria toxin receptor-based mouse models to ablate dendritic cells

Dendritic cells (DCs) are key regulators of innate and adaptive immunity. Our understanding of immune function has benefited greatly from mouse models allowing for selective ablation of DCs. Many such models rely on transgenic diphtheria toxin receptor (DTR) expression driven by DC-restricted promot...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: van Blijswijk, Janneke, Schraml, Barbara U., Rogers, Neil C., Whitney, Paul G., Zelenay, Santiago, Acton, Sophie E., Sousa, Caetano Reis e
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272857/
https://ncbi.nlm.nih.gov/pubmed/25411201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401999
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