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Oncogenic Transformation of Dendritic Cells and Their Precursors Leads to Rapid Cancer Development in Mice

Dendritic cells (DCs) are powerful APCs that can induce Ag-specific adaptive immune responses and are increasingly recognized as important players in innate immunity to both infection and malignancy. Interestingly, although there are multiple described hematological malignancies, DC cancers are rare...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Böttcher, Jan P., Zelenay, Santiago, Rogers, Neil C., Helft, Julie, Schraml, Barbara U., Reis e Sousa, Caetano
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635568/
https://ncbi.nlm.nih.gov/pubmed/26459350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500889
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