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Oncogenic Transformation of Dendritic Cells and Their Precursors Leads to Rapid Cancer Development in Mice

Dendritic cells (DCs) are powerful APCs that can induce Ag-specific adaptive immune responses and are increasingly recognized as important players in innate immunity to both infection and malignancy. Interestingly, although there are multiple described hematological malignancies, DC cancers are rare...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Böttcher, Jan P., Zelenay, Santiago, Rogers, Neil C., Helft, Julie, Schraml, Barbara U., Reis e Sousa, Caetano
Format: Artigo
Langue:Inglês
Publié: AAI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635568/
https://ncbi.nlm.nih.gov/pubmed/26459350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500889
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