Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats

BACKGROUND: Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease characterized by cellular infiltration into the joints, hyperproliferation of synovial cells and bone damage. Available treatments for RA only induce remission in around 30% of the patients, have important advers...

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Udgivet i:PLoS One
Main Authors: Cascão, Rita, Vidal, Bruno, Lopes, Inês P., Paisana, Eunice, Rino, José, Moita, Luis F., Fonseca, João E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676706/
https://ncbi.nlm.nih.gov/pubmed/26658436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142448
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