Thrombotic Microangiopathies: Multimers, Metalloprotease, and Beyond

Por Moake, Joel
Publicado no Clin Transl Sci (2009)

Thrombotic thrombocytopenic purpura: survival by "giving a dam".

Por Moake, Joel L.
Publicado em 2004

Assembly and Activation of Alternative Complement Components on Endothelial Cell-Anchored Ultra-Large Von Willebrand Factor Links Complement and Hemostasis-Thrombosis

Por Turner, Nancy A., Moake, Joel
Publicado em 2013

Factor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings

Por Turner, Nancy A., Moake, Joel L.
Publicado no PLoS One (2015)

Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage

Por Turner, Nancy A., Nolasco, Leticia, Ruggeri, Zaverio M., Moake, Joel L.
Publicado em 2009

Interaction of Shiga Toxin with the A-domains and Multimers of von Willebrand Factor

Por Lo, Nathan C., Turner, Nancy A., Cruz, Miguel A., Moake, Joel
Publicado em 2013

Complement activation in thrombotic microangiopathies

Por Feng, Shuju, Kroll, Michael H., Nolasco, Leticia, Moake, Joel, Afshar-Kharghan, Vahid
Publicado em 2012

Regulatory Components of the Alternative Complement Pathway in Endothelial Cell Cytoplasm, Factor H and Factor I, Are Not Packaged in Weibel-Palade Bodies

Por Turner, Nancy A., Sartain, Sarah E., Hui, Shiu-Ki, Moake, Joel L.
Publicado no PLoS One (2015)

Antibody Inhibitors to von Willebrand Factor Metalloproteinase and Increased Binding of von Willebrand Factor to Platelets in Ticlopidine-Associated Thrombotic Thrombocytopenic Pur...

Por Tsai, Han-Mou, Rice, Lawrence, Sarode, Ravindra, Chow, Thomas W., Moake, Joel L.
Publicado em 2000

Acquired von Willebrand syndrome associated with left ventricular assist device

Por Nascimbene, Angelo, Neelamegham, Sriram, Frazier, O. H., Moake, Joel L., Dong, Jing-fei
Publicado no Blood (2016)

Laminin Peptide-Immobilized Hydrogels Modulate Valve Endothelial Cell Hemostatic Regulation

Por Balaoing, Liezl Rae, Post, Allison Davis, Lin, Adam Yuh, Tseng, Hubert, Moake, Joel L., Grande-Allen, K. Jane
Publicado no PLoS One (2015)

Hemolytic uremic syndrome–associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers

Por Nolasco, Leticia H., Turner, Nancy A., Bernardo, Aubrey, Tao, Zhenyin, Cleary, Thomas G., Dong, Jing-fei, Moake, Joel L.
Publicado em 2005

COVALENT REGULATION OF ULVWF STRING FORMATION AND ELONGATION ON ENDOTHELIAL CELLS UNDER FLOW CONDITIONS

Por Li, Ying, Choi, Hiuwan, Zhou, Zhou, Nolasco, Leticia, Pownall, Henry J., Voorberg, Jan, Moake, Joel L., Dong, Jing-fei
Publicado em 2008

N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice

Por Chen, Junmei, Reheman, Adili, Gushiken, Francisca C., Nolasco, Leticia, Fu, Xiaoyun, Moake, Joel L., Ni, Heyu, López, José A.
Publicado em 2011

Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions

Por Tao, Zhenyin, Peng, Yuandong, Nolasco, Leticia, Cal, Santiago, Lopez-Otin, Carlos, Li, Renhao, Moake, Joel L., López, José A., Dong, Jing-fei
Publicado em 2005

In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology

Por Tsai, Michelle, Kita, Ashley, Leach, Joseph, Rounsevell, Ross, Huang, James N., Moake, Joel, Ware, Russell E., Fletcher, Daniel A., Lam, Wilbur A.
Publicado em 2011

Disulfide Bond Reduction of Von Willebrand Factor by ADAMTS-13

Por Yeh, Hui-Chun, Zhou, Zhou, Choi, Hiuwan, Tekeoglu, Senem, May, William, Wang, Christina, Turner, Nancy, Scheiflinger, Friedrich, Moake, Joel L., Dong, Jing-fei
Publicado em 2010

Mechanical Activation of a Multimeric Adhesive Protein through Domain Conformational Change

Por Wijeratne, Sithara S., Botello, Eric, Yeh, Hui-Chun, Zhou, Zhou, Bergeron, Angela, Frey, Eric W., Patel, Jay M., Moake, Joel, Dong, Jing-fei, Kiang, Ching-Hwa
Publicado em 2013

Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989–2008)

Por Zakarija, Anaadriana, Kwaan, Hau C., Moake, Joel L., Bandarenko, Nicholas, Pandey, Dilip K., McKoy, June M., Yarnold, Paul R., Raisch, Dennis W., Winters, Jeffrey L., Raife, Thomas J., Cursio, John F., Luu, Thanh Ha, Richey, Elizabeth A., Fisher, Matthew J., Ortel, Thomas L., Tallman, Martin S., Zheng, X. Long, Matsumoto, Masanori, Fujimura, Yoshihiro, Bennett, Charles L.
Publicado em 2009