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Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989–2008)
Thrombotic thrombocytopenic purpura (TTP) is a fulminant disease characterized by platelet aggregates, thrombocytopenia, renal insufficiency, neurologic changes, and mechanical injury to erythrocytes. Most idiopathic cases of TTP are characterized by a deficiency of ADAMTS13 (a disintegrin and metal...
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2009
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3500614/ https://ncbi.nlm.nih.gov/pubmed/19180126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.613 |
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