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Assembly and Activation of Alternative Complement Components on Endothelial Cell-Anchored Ultra-Large Von Willebrand Factor Links Complement and Hemostasis-Thrombosis

BACKGROUND: Vascular endothelial cells (ECs) express and release protein components of the complement pathways, as well as secreting and anchoring ultra-large von Willebrand factor (ULVWF) multimers in long string-like structures that initiate platelet adhesion during hemostasis and thrombosis. The...

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Detalhes bibliográficos
Main Authors: Turner, Nancy A., Moake, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612042/
https://ncbi.nlm.nih.gov/pubmed/23555663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059372
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