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Complement Component C3 Binds to the A3 Domain of von Willebrand Factor
von Willebrand factor (VWF) is a multimeric protein composed of monomeric subunits (∼280 kD) linked by disulfide bonds. During hemostasis and thrombosis, ultralarge (UL) VWF (ULVWF) multimers initiate platelet adhesion. In vitro, human C3 binds to ULVWF multimeric strings secreted by and anchored to...
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| Publicado no: | TH Open |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Georg Thieme Verlag KG
2018
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6508891/ https://ncbi.nlm.nih.gov/pubmed/31080944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1672189 |
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