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The role of von Willebrand factor in thrombus formation

Von Willebrand factor (VWF) is a large multimeric glycoprotein produced in endothelial cells and megakaryocytes and present in subendothelial matrix, blood plasma and platelets. VWF mediates adhesion and aggregation of platelets at sites of vascular injury, processes that are critical for both haemo...

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Bibliografiske detaljer
Hovedforfatter: Ruggeri, Zaverio M
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702526/
https://ncbi.nlm.nih.gov/pubmed/17493665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2007.03.011
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