In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology

In hematologic diseases, such as sickle cell disease (SCD) and hemolytic uremic syndrome (HUS), pathological biophysical interactions among blood cells, endothelial cells, and soluble factors lead to microvascular occlusion and thrombosis. Here, we report an in vitro “endothelialized” microfluidic m...

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Autores principales: Tsai, Michelle, Kita, Ashley, Leach, Joseph, Rounsevell, Ross, Huang, James N., Moake, Joel, Ware, Russell E., Fletcher, Daniel A., Lam, Wilbur A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2011
Materias:
Technical Advance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248292/
https://ncbi.nlm.nih.gov/pubmed/22156199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58753
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