Analysis of an Ethylnitrosourea-generated Mouse Mutation Defines a Cell Intrinsic Role of Nuclear Factor κB2 in Regulating Circulating B Cell Numbers

Por Miosge, Lisa A., Blasioli, Julie, Blery, Mathieu, Goodnow, Christopher C.
Publicado em 2002

Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-κB in B cell clonal anergy

Por Bléry, Mathieu, Tze, Lina, Miosge, Lisa A., Jun, Jesse E., Goodnow, Christopher C.
Publicado em 2006

Quantitative reduction of the T cell receptor adapter protein SLP-76 unbalances immunity and immune regulation

Por Siggs, Owen M., Miosge, Lisa A., Daley, Stephen R., Asquith, Kelly, Foster, Paul S., Liston, Adrian, Goodnow, Christopher C.
Publicado no J Immunol (2015)

Opposing functions of Zap70 for immunity and tolerance titrate differentially in response to inherited single nucleotide substitutions

Por Siggs, Owen M, Miosge, Lisa A, Yates, Adèle L, Kucharska, Edyta M, Sheahan, Daniel, Brdicka, Tomas, Weiss, Arthur, Liston, Adrian, Goodnow, Christopher C
Publicado em 2007

Delayed control of herpes simplex virus infection and impaired CD4(+) T cell migration to the skin in mouse models of DOCK8 deficiency

Por Flesch, Inge EA, Randall, Katrina L, Hollett, Natasha A, Law, HseiDi, Miosge, Lisa A, Sontani, Yovina, Goodnow, Christopher C, Tscharke, David C
Publicado no Immunol Cell Biol (2015)

Finding new immune regulatory genes by ENU mutagenesis

Por Enders, Anselm, Bergmann, Hannes, Yabas, Mehmet, Andrews, T Dan, Whittle, Belinda, Field, Mathew, Balakishnan, Bhavani, Sontani, Yovina, Miosge, Lisa, Sjollema, Geoff, Read, Stuart, Bertram, Ed, Goodnow, Chris C
Publicado em 2012

A Novel Mutation in Nucleoporin 35 Causes Murine Degenerative Colonic Smooth Muscle Myopathy

Por Parish, Ian A., Stamp, Lincon A., Lorenzo, Ayla May D., Fowler, Suzanne M., Sontani, Yovina, Miosge, Lisa A., Howard, Debbie R., Goodnow, Christopher C., Young, Heather M., Furness, John B.
Publicado no Am J Pathol (2016)

Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes

Por Enders, Anselm, Short, Alanna, Miosge, Lisa A., Bergmann, Hannes, Sontani, Yovina, Bertram, Edward M., Whittle, Belinda, Balakishnan, Bhavani, Yoshida, Kaoru, Sjollema, Geoff, Field, Matthew A., Andrews, T. Daniel, Hagiwara, Hiromi, Goodnow, Christopher C.
Publicado em 2014

Comparison of predicted and actual consequences of missense mutations

Por Miosge, Lisa A., Field, Matthew A., Sontani, Yovina, Cho, Vicky, Johnson, Simon, Palkova, Anna, Balakishnan, Bhavani, Liang, Rong, Zhang, Yafei, Lyon, Stephen, Beutler, Bruce, Whittle, Belinda, Bertram, Edward M., Enders, Anselm, Goodnow, Christopher C., Andrews, T. Daniel
Publicado no Proc Natl Acad Sci U S A (2015)

Unlocking the Bottleneck in Forward Genetics Using Whole-Genome Sequencing and Identity by Descent to Isolate Causative Mutations

Por Bull, Katherine R., Rimmer, Andrew J., Siggs, Owen M., Miosge, Lisa A., Roots, Carla M., Enders, Anselm, Bertram, Edward M., Crockford, Tanya L., Whittle, Belinda, Potter, Paul K., Simon, Michelle M., Mallon, Ann-Marie, Brown, Steve D. M., Beutler, Bruce, Goodnow, Christopher C., Lunter, Gerton, Cornall, Richard J.
Publicado em 2013

B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8(−) dendritic cells require the intramembrane endopeptidase SPPL2A

Por Bergmann, Hannes, Yabas, Mehmet, Short, Alanna, Miosge, Lisa, Barthel, Nadine, Teh, Charis E., Roots, Carla M., Bull, Katherine R., Jeelall, Yogesh, Horikawa, Keisuke, Whittle, Belinda, Balakishnan, Bhavani, Sjollema, Geoff, Bertram, Edward M., Mackay, Fabienne, Rimmer, Andrew J., Cornall, Richard J., Field, Matthew A., Andrews, T. Daniel, Goodnow, Christopher C., Enders, Anselm
Publicado em 2013

Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios(+) T cells and autoantibodies

Por Daley, Stephen R, Coakley, Kristen M, Hu, Daniel Y, Randall, Katrina L, Jenne, Craig N, Limnander, Andre, Myers, Darienne R, Polakos, Noelle K, Enders, Anselm, Roots, Carla, Balakishnan, Bhavani, Miosge, Lisa A, Sjollema, Geoff, Bertram, Edward M, Field, Matthew A, Shao, Yunli, Andrews, T Daniel, Whittle, Belinda, Barnes, S Whitney, Walker, John R, Cyster, Jason G, Goodnow, Christopher C, Roose, Jeroen P
Publicado em 2013