Development of humanized mouse models to study human malaria parasite infection

Por Vaughan, Ashley M, Kappe, Stefan HI, Ploss, Alexander, Mikolajczak, Sebastian A
Publicado em 2012

Of men in mice: the success and promise of humanized mouse models for human malaria parasite infections

Por Kaushansky, Alexis, Mikolajczak, Sebastian A., Vignali, Marissa, Kappe, Stefan H.I.
Publicado em 2014

Plasmodium yoelii Macrophage Migration Inhibitory Factor Is Necessary for Efficient Liver-Stage Development

Por Miller, Jessica L., Harupa, Anke, Kappe, Stefan H. I., Mikolajczak, Sebastian A.
Publicado em 2012

The Modulation of CD40 Ligand Signaling by Transmembrane CD28 Splice Variant in Human T Cells

Por Mikolajczak, Sebastian A., Ma, Bruce Y., Yoshida, Tetsuya, Yoshida, Ryoko, Kelvin, David J., Ochi, Atsuo
Publicado em 2004

Neuroimmunological Blood Brain Barrier Opening in Experimental Cerebral Malaria

Por Nacer, Adela, Movila, Alexandru, Baer, Kerstin, Mikolajczak, Sebastian A., Kappe, Stefan H. I., Frevert, Ute
Publicado em 2012

Plasmodium yoelii Sporozoites with Simultaneous Deletion of P52 and P36 Are Completely Attenuated and Confer Sterile Immunity against Infection

Por Labaied, Mehdi, Harupa, Anke, Dumpit, Ronald F., Coppens, Isabelle, Mikolajczak, Sebastian A., Kappe, Stefan H. I.
Publicado em 2007

A dispensable Plasmodium locus for stable transgene expression

Por Jacobs-Lorena, Vanessa Y., Mikolajczak, Sebastian A., Labaied, Mehdi, Vaughan, Ashley M., Kappe, Stefan H.I.
Publicado em 2010

Perturbations of Plasmodium Puf2 Expression and RNA-seq of Puf2-Deficient Sporozoites Reveal a Critical Role in Maintaining RNA Homeostasis and Parasite Transmissibility

Por Lindner, Scott E., Mikolajczak, Sebastian A., Vaughan, Ashley M., Moon, Wonjong, Joyce, Brad R., Sullivan, William J., Kappe, Stefan H. I.
Publicado em 2013

Cyclic GMP Balance Is Critical for Malaria Parasite Transmission from the Mosquito to the Mammalian Host

Por Lakshmanan, Viswanathan, Fishbaugher, Matthew E., Morrison, Bob, Baldwin, Michael, Macarulay, Michael, Vaughan, Ashley M., Mikolajczak, Sebastian A., Kappe, Stefan H. I.
Publicado no mBio (2015)

Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection

Por Aly, Ahmed S I, Mikolajczak, Sebastian A, Rivera, Hilda Silva, Camargo, Nelly, Jacobs-Lorena, Vanessa, Labaied, Mehdi, Coppens, Isabelle, Kappe, Stefan H I
Publicado em 2008

Complete Plasmodium falciparum liver-stage development in liver-chimeric mice

Por Vaughan, Ashley M., Mikolajczak, Sebastian A., Wilson, Elizabeth M., Grompe, Markus, Kaushansky, Alexis, Camargo, Nelly, Bial, John, Ploss, Alexander, Kappe, Stefan H.I.
Publicado em 2012

Interrogation of infected hepatocyte signaling reveals that suppression of host p53 is critical for Plasmodium liver stage infection

Por Kaushansky, Alexis, Ye, Albert S., Austin, Laura S., Mikolajczak, Sebastian A., Vaughan, Ashley M., Camargo, Nelly, Metzger, Peter G., Douglass, Alyse N., MacBeath, Gavin, Kappe, Stefan H.I.
Publicado em 2013

Susceptibility to Plasmodium yoelii Preerythrocytic Infection in BALB/c Substrains Is Determined at the Point of Hepatocyte Invasion

Por Kaushansky, Alexis, Austin, Laura S., Mikolajczak, Sebastian A., Lo, Fang Y., Miller, Jessica L., Douglass, Alyse N., Arang, Nadia, Vaughan, Ashley M., Gardner, Malcolm J., Kappe, Stefan H. I.
Publicado no Infect Immun (2014)

Disruption of the Plasmodium falciparum liver-stage antigen-1 locus causes a differentiation defect in late liver-stage parasites

Por Mikolajczak, Sebastian A., Sacci, John B., De La Vega, Patricia, Camargo, Nelly, VanBuskirk, Kelly, Krzych, Urszula, Cao, Jun, Jacobs-Lorena, Marcelo, Cowman, Alan F., Kappe, Stefan H. I.
Publicado em 2011

Short-Lived Effector CD8 T Cells Induced by Genetically Attenuated Malaria Parasite Vaccination Express CD11c

Por Cooney, Laura A., Gupta, Megha, Thomas, Sunil, Mikolajczak, Sebastian, Choi, Kimberly Y., Gibson, Claire, Jang, Ihn K., Danziger, Sam, Aitchison, John, Gardner, Malcolm J., Kappe, Stefan H. I., Wang, Ruobing
Publicado em 2013

Model for In Vivo Assessment of Humoral Protection against Malaria Sporozoite Challenge by Passive Transfer of Monoclonal Antibodies and Immune Serum

Por Sack, Brandon K., Miller, Jessica L., Vaughan, Ashley M., Douglass, Alyse, Kaushansky, Alexis, Mikolajczak, Sebastian, Coppi, Alida, Gonzalez-Aseguinolaza, Gloria, Tsuji, Moriya, Zavala, Fidel, Sinnis, Photini, Kappe, Stefan H. I.
Publicado em 2014

Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites

Por Douglass, Alyse N, Kain, Heather S, Abdullahi, Marian, Arang, Nadia, Austin, Laura S, Mikolajczak, Sebastian A, Billman, Zachary P, Hume, Jen C C, Murphy, Sean C, Kappe, Stefan H I, Kaushansky, Alexis
Publicado no Mol Ther (2015)

A Next-generation Genetically Attenuated Plasmodium falciparum Parasite Created by Triple Gene Deletion

Por Mikolajczak, Sebastian A, Lakshmanan, Viswanathan, Fishbaugher, Matthew, Camargo, Nelly, Harupa, Anke, Kaushansky, Alexis, Douglass, Alyse N, Baldwin, Michael, Healer, Julie, O'Neill, Matthew, Phuong, Thuan, Cowman, Alan, Kappe, Stefan H I
Publicado no Mol Ther (2014)

Distinct Malaria Parasite Sporozoites Reveal Transcriptional Changes That Cause Differential Tissue Infection Competence in the Mosquito Vector and Mammalian Host

Por Mikolajczak, Sebastian A., Silva-Rivera, Hilda, Peng, Xinxia, Tarun, Alice S., Camargo, Nelly, Jacobs-Lorena, Vanessa, Daly, Thomas M., Bergman, Lawrence W., de la Vega, Patricia, Williams, Jack, Aly, Ahmed S. I., Kappe, Stefan H. I.
Publicado em 2008

Proteogenomic analysis of the total and surface-exposed proteomes of Plasmodium vivax salivary gland sporozoites

Por Swearingen, Kristian E., Lindner, Scott E., Flannery, Erika L., Vaughan, Ashley M., Morrison, Robert D., Patrapuvich, Rapatbhorn, Koepfli, Cristian, Muller, Ivo, Jex, Aaron, Moritz, Robert L., Kappe, Stefan H. I., Sattabongkot, Jetsumon, Mikolajczak, Sebastian A.
Publicado no PLoS Negl Trop Dis (2017)