Model for In Vivo Assessment of Humoral Protection against Malaria Sporozoite Challenge by Passive Transfer of Monoclonal Antibodies and Immune Serum

Evidence from clinical trials of malaria vaccine candidates suggests that both cell-mediated and humoral immunity to pre-erythrocytic parasite stages can provide protection against infection. Novel pre-erythrocytic antibody (Ab) targets could be key to improving vaccine formulations, which are curre...

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Główni autorzy: Sack, Brandon K., Miller, Jessica L., Vaughan, Ashley M., Douglass, Alyse, Kaushansky, Alexis, Mikolajczak, Sebastian, Coppi, Alida, Gonzalez-Aseguinolaza, Gloria, Tsuji, Moriya, Zavala, Fidel, Sinnis, Photini, Kappe, Stefan H. I.
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology 2014
Hasła przedmiotowe:
Microbial Immunity and Vaccines
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911395/
https://ncbi.nlm.nih.gov/pubmed/24478094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01249-13
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