Model for In Vivo Assessment of Humoral Protection against Malaria Sporozoite Challenge by Passive Transfer of Monoclonal Antibodies and Immune Serum

Evidence from clinical trials of malaria vaccine candidates suggests that both cell-mediated and humoral immunity to pre-erythrocytic parasite stages can provide protection against infection. Novel pre-erythrocytic antibody (Ab) targets could be key to improving vaccine formulations, which are curre...

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Autores principales: Sack, Brandon K., Miller, Jessica L., Vaughan, Ashley M., Douglass, Alyse, Kaushansky, Alexis, Mikolajczak, Sebastian, Coppi, Alida, Gonzalez-Aseguinolaza, Gloria, Tsuji, Moriya, Zavala, Fidel, Sinnis, Photini, Kappe, Stefan H. I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911395/
https://ncbi.nlm.nih.gov/pubmed/24478094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01249-13
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