Model for In Vivo Assessment of Humoral Protection against Malaria Sporozoite Challenge by Passive Transfer of Monoclonal Antibodies and Immune Serum

Evidence from clinical trials of malaria vaccine candidates suggests that both cell-mediated and humoral immunity to pre-erythrocytic parasite stages can provide protection against infection. Novel pre-erythrocytic antibody (Ab) targets could be key to improving vaccine formulations, which are curre...

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Bibliographic Details
Main Authors: Sack, Brandon K., Miller, Jessica L., Vaughan, Ashley M., Douglass, Alyse, Kaushansky, Alexis, Mikolajczak, Sebastian, Coppi, Alida, Gonzalez-Aseguinolaza, Gloria, Tsuji, Moriya, Zavala, Fidel, Sinnis, Photini, Kappe, Stefan H. I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911395/
https://ncbi.nlm.nih.gov/pubmed/24478094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01249-13
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