Model for In Vivo Assessment of Humoral Protection against Malaria Sporozoite Challenge by Passive Transfer of Monoclonal Antibodies and Immune Serum

Evidence from clinical trials of malaria vaccine candidates suggests that both cell-mediated and humoral immunity to pre-erythrocytic parasite stages can provide protection against infection. Novel pre-erythrocytic antibody (Ab) targets could be key to improving vaccine formulations, which are curre...

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Detalhes bibliográficos
Main Authors: Sack, Brandon K., Miller, Jessica L., Vaughan, Ashley M., Douglass, Alyse, Kaushansky, Alexis, Mikolajczak, Sebastian, Coppi, Alida, Gonzalez-Aseguinolaza, Gloria, Tsuji, Moriya, Zavala, Fidel, Sinnis, Photini, Kappe, Stefan H. I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911395/
https://ncbi.nlm.nih.gov/pubmed/24478094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01249-13
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