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Plasmodium yoelii Sporozoites with Simultaneous Deletion of P52 and P36 Are Completely Attenuated and Confer Sterile Immunity against Infection

Malaria infection starts when sporozoites are transmitted to the mammalian host during a mosquito bite. Sporozoites enter the blood circulation, reach the liver, and infect hepatocytes. The formation of a parasitophorous vacuole (PV) establishes their intracellular niche. Recently, two members of th...

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Bibliographische Detailangaben
Hauptverfasser: Labaied, Mehdi, Harupa, Anke, Dumpit, Ronald F., Coppens, Isabelle, Mikolajczak, Sebastian A., Kappe, Stefan H. I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951999/
https://ncbi.nlm.nih.gov/pubmed/17517871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00225-07
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