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Chemical Attenuation of Plasmodium berghei Sporozoites Induces Sterile Immunity in Mice
Radiation and genetic attenuation of Plasmodium sporozoites are two approaches for whole-organism vaccines that protect against malaria. We evaluated chemical attenuation of sporozoites as an alternative vaccine strategy. Sporozoites were treated with the DNA sequence-specific alkylating agent centa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258828/ https://ncbi.nlm.nih.gov/pubmed/18174336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01399-07 |
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