A set of microRNAs coordinately controls tumorigenesis, invasion, and metastasis

by Michael, Iacovos P., Saghafinia, Sadegh, Hanahan, Douglas
Published in Proc Natl Acad Sci U S A (2019)

Simple piggyBac transposon-based mammalian cell expression system for inducible protein production

by Li, Zhijie, Michael, Iacovos P., Zhou, Dongxia, Nagy, Andras, Rini, James M.
Published 2013

KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome

by Furio, Laetitia, Pampalakis, Georgios, Michael, Iacovos P., Nagy, Andras, Sotiropoulou, Georgia, Hovnanian, Alain
Published in PLoS Genet (2015)

Angiopoietin-1 deficiency increases tumor metastasis in mice

by Michael, Iacovos P., Orebrand, Martina, Lima, Marta, Pereira, Beatriz, Volpert, Olga, Quaggin, Susan E., Jeansson, Marie
Published in BMC Cancer (2017)

Cancer cells retrace a stepwise differentiation program during malignant progression

by Saghafinia, Sadegh, Homicsko, Krisztian, Di Domenico, Annunziata, Wullschleger, Stephan, Perren, Aurel, Marinoni, Ilaria, Ciriello, Giovanni, Michael, Iacovos P., Hanahan, Douglas
Published in Cancer Discov (2021)

Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity

by Phelps, Edward A., Cianciaruso, Chiara, Michael, Iacovos P., Pasquier, Miriella, Kanaani, Jamil, Nano, Rita, Lavallard, Vanessa, Billestrup, Nils, Hubbell, Jeffrey A., Baekkeskov, Steinunn
Published in Diabetes (2016)

Highly efficient site-specific transgenesis in cancer cell lines

by Michael, Iacovos P, Monetti, Claudio, Chiu, Anthony C, Zhang, Puzheng, Baba, Takeshi, Nishino, Koichiro, Agha-Mohammadi, Siamak, Woltjen, Knut, Sung, Hoon-Ki, Nagy, Andras
Published 2012

Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD

by Cortez, Eliane, Gladh, Hanna, Braun, Sebastian, Bocci, Matteo, Cordero, Eugenia, Björkström, Niklas K., Miyazaki, Hideki, Michael, Iacovos P., Eriksson, Ulf, Folestad, Erika, Pietras, Kristian
Published in Proc Natl Acad Sci U S A (2016)

Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation

by Allen, Elizabeth, Jabouille, Arnaud, Rivera, Lee B., Lodewijckx, Inge, Missiaen, Rindert, Steri, Veronica, Feyen, Kevin, Tawney, Jaime, Hanahan, Douglas, Michael, Iacovos P., Bergers, Gabriele
Published in Sci Transl Med (2017)

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

by Woltjen, Knut, Michael, Iacovos P., Mohseni, Paria, Desai, Ridham, Mileikovsky, Maria, Hämäläinen, Riikka, Cowling, Rebecca, Wang, Wei, Liu, Pentao, Gertsenstein, Marina, Kaji, Keisuke, Sung, Hoon-Ki, Nagy, Andras
Published 2009

Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting

by Westenskow, Peter D., Kurihara, Toshihide, Aguilar, Edith, Scheppke, Elizabeth L., Moreno, Stacey K., Wittgrove, Carli, Marchetti, Valentina, Michael, Iacovos P., Anand, Sudarshan, Nagy, Andras, Cheresh, David, Friedlander, Martin
Published 2013

Vascular targeting of LIGHT normalizes blood vessels in primary brain cancer and induces intratumoural high endothelial venules

by He, Bo, Jabouille, Arnaud, Steri, Veronica, Johansson-Percival, Anna, Michael, Iacovos P, Kotamraju, Venkata Ramana, Junckerstorff, Reimar, Nowak, Anna K, Hamzah, Juliana, Lee, Gabriel, Bergers, Gabriele, Ganss, Ruth
Published in J Pathol (2018)

A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells

by Yang, Xiaojing, Nanayakkara, Jina, Claypool, Duncan, Saghafinia, Sadegh, Wong, Justin J. M., Xu, Minqi, Wang, Xiantao, Nicol, Christopher J. B., Michael, Iacovos P., Hafner, Markus, Yang, Xiaolong, Renwick, Neil
Published in Sci Rep (2021)

Synaptic proximity enables NMDAR signaling to promote brain metastasis

by Zeng, Qiqun, Michael, Iacovos P., Zhang, Peng, Saghafinia, Sadegh, Knott, Graham, Jiao, Wei, McCabe, Brian D., Galván, José A., Robinson, Hugh P. C., Zlobec, Inti, Ciriello, Giovanni, Hanahan, Douglas
Published in Nature (2019)

VEGF regulates local inhibitory complement proteins in the eye and kidney

by Keir, Lindsay S., Firth, Rachel, Aponik, Lyndsey, Feitelberg, Daniel, Sakimoto, Susumu, Aguilar, Edith, Welsh, Gavin I., Richards, Anna, Usui, Yoshihiko, Satchell, Simon C., Kuzmuk, Valeryia, Coward, Richard J., Goult, Jonathan, Bull, Katherine R., Sharma, Ruchi, Bharti, Kapil, Westenskow, Peter D., Michael, Iacovos P., Saleem, Moin A., Friedlander, Martin
Published in J Clin Invest (2016)

Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye

by Michael, Iacovos P, Westenskow, Peter D, Hacibekiroglu, Sabiha, Greenwald, Alissa Cohen, Ballios, Brian G, Kurihara, Toshihide, Li, Zhijie, Warren, Carmen M, Zhang, Puzheng, Aguilar, Edith, Donaldson, Laura, Marchetti, Valentina, Baba, Takeshi, Hussein, Samer M, Sung, Hoon-Ki, Iruela-Arispe, M Luisa, Rini, James M, van der Kooy, Derek, Friedlander, Martin, Nagy, Andras
Published 2014

MBNL proteins repress embryonic stem cell-specific alternative splicing and reprogramming

by Han, Hong, Irimia, Manuel, Ross, P. Joel, Sung, Hoon-Ki, Alipanahi, Babak, David, Laurent, Golipour, Azadeh, Gabut, Mathieu, Michael, Iacovos P., Nachman, Emil N., Wang, Eric, Trcka, Dan, Thompson, Tadeo, O’Hanlon, Dave, Slobodeniuc, Valentina, Barbosa-Morais, Nuno L., Burge, Christopher B., Moffat, Jason, Frey, Brendan J., Nagy, Andras, Ellis, James, Wrana, Jeffrey L., Blencowe, Benjamin J.
Published 2013