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piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
Transgenic expression of just four defined transcription factors (c-Myc, Klf4, Oct4, and Sox2) is sufficient to reprogram somatic cells to a pluripotent state(1-4). The resulting induced pluripotent stem (iPS) cells resemble ES cells in their properties and potential to differentiate into a spectrum...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758996/ https://ncbi.nlm.nih.gov/pubmed/19252478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07863 |
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