טוען...
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
Transgenic expression of just four defined transcription factors (c-Myc, Klf4, Oct4, and Sox2) is sufficient to reprogram somatic cells to a pluripotent state(1-4). The resulting induced pluripotent stem (iPS) cells resemble ES cells in their properties and potential to differentiate into a spectrum...
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| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758996/ https://ncbi.nlm.nih.gov/pubmed/19252478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07863 |
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