A set of microRNAs coordinately controls tumorigenesis, invasion, and metastasis

Por Michael, Iacovos P., Saghafinia, Sadegh, Hanahan, Douglas
Publicado no Proc Natl Acad Sci U S A (2019)

Simple piggyBac transposon-based mammalian cell expression system for inducible protein production

Por Li, Zhijie, Michael, Iacovos P., Zhou, Dongxia, Nagy, Andras, Rini, James M.
Publicado em 2013

KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome

Por Furio, Laetitia, Pampalakis, Georgios, Michael, Iacovos P., Nagy, Andras, Sotiropoulou, Georgia, Hovnanian, Alain
Publicado no PLoS Genet (2015)

Angiopoietin-1 deficiency increases tumor metastasis in mice

Por Michael, Iacovos P., Orebrand, Martina, Lima, Marta, Pereira, Beatriz, Volpert, Olga, Quaggin, Susan E., Jeansson, Marie
Publicado no BMC Cancer (2017)

Cancer cells retrace a stepwise differentiation program during malignant progression

Por Saghafinia, Sadegh, Homicsko, Krisztian, Di Domenico, Annunziata, Wullschleger, Stephan, Perren, Aurel, Marinoni, Ilaria, Ciriello, Giovanni, Michael, Iacovos P., Hanahan, Douglas
Publicado no Cancer Discov (2021)

Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity

Por Phelps, Edward A., Cianciaruso, Chiara, Michael, Iacovos P., Pasquier, Miriella, Kanaani, Jamil, Nano, Rita, Lavallard, Vanessa, Billestrup, Nils, Hubbell, Jeffrey A., Baekkeskov, Steinunn
Publicado no Diabetes (2016)

Highly efficient site-specific transgenesis in cancer cell lines

Por Michael, Iacovos P, Monetti, Claudio, Chiu, Anthony C, Zhang, Puzheng, Baba, Takeshi, Nishino, Koichiro, Agha-Mohammadi, Siamak, Woltjen, Knut, Sung, Hoon-Ki, Nagy, Andras
Publicado em 2012

Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD

Por Cortez, Eliane, Gladh, Hanna, Braun, Sebastian, Bocci, Matteo, Cordero, Eugenia, Björkström, Niklas K., Miyazaki, Hideki, Michael, Iacovos P., Eriksson, Ulf, Folestad, Erika, Pietras, Kristian
Publicado no Proc Natl Acad Sci U S A (2016)

Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation

Por Allen, Elizabeth, Jabouille, Arnaud, Rivera, Lee B., Lodewijckx, Inge, Missiaen, Rindert, Steri, Veronica, Feyen, Kevin, Tawney, Jaime, Hanahan, Douglas, Michael, Iacovos P., Bergers, Gabriele
Publicado no Sci Transl Med (2017)

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

Por Woltjen, Knut, Michael, Iacovos P., Mohseni, Paria, Desai, Ridham, Mileikovsky, Maria, Hämäläinen, Riikka, Cowling, Rebecca, Wang, Wei, Liu, Pentao, Gertsenstein, Marina, Kaji, Keisuke, Sung, Hoon-Ki, Nagy, Andras
Publicado em 2009

Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting

Por Westenskow, Peter D., Kurihara, Toshihide, Aguilar, Edith, Scheppke, Elizabeth L., Moreno, Stacey K., Wittgrove, Carli, Marchetti, Valentina, Michael, Iacovos P., Anand, Sudarshan, Nagy, Andras, Cheresh, David, Friedlander, Martin
Publicado em 2013

Vascular targeting of LIGHT normalizes blood vessels in primary brain cancer and induces intratumoural high endothelial venules

Por He, Bo, Jabouille, Arnaud, Steri, Veronica, Johansson-Percival, Anna, Michael, Iacovos P, Kotamraju, Venkata Ramana, Junckerstorff, Reimar, Nowak, Anna K, Hamzah, Juliana, Lee, Gabriel, Bergers, Gabriele, Ganss, Ruth
Publicado no J Pathol (2018)

A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells

Por Yang, Xiaojing, Nanayakkara, Jina, Claypool, Duncan, Saghafinia, Sadegh, Wong, Justin J. M., Xu, Minqi, Wang, Xiantao, Nicol, Christopher J. B., Michael, Iacovos P., Hafner, Markus, Yang, Xiaolong, Renwick, Neil
Publicado no Sci Rep (2021)

Synaptic proximity enables NMDAR signaling to promote brain metastasis

Por Zeng, Qiqun, Michael, Iacovos P., Zhang, Peng, Saghafinia, Sadegh, Knott, Graham, Jiao, Wei, McCabe, Brian D., Galván, José A., Robinson, Hugh P. C., Zlobec, Inti, Ciriello, Giovanni, Hanahan, Douglas
Publicado no Nature (2019)

VEGF regulates local inhibitory complement proteins in the eye and kidney

Por Keir, Lindsay S., Firth, Rachel, Aponik, Lyndsey, Feitelberg, Daniel, Sakimoto, Susumu, Aguilar, Edith, Welsh, Gavin I., Richards, Anna, Usui, Yoshihiko, Satchell, Simon C., Kuzmuk, Valeryia, Coward, Richard J., Goult, Jonathan, Bull, Katherine R., Sharma, Ruchi, Bharti, Kapil, Westenskow, Peter D., Michael, Iacovos P., Saleem, Moin A., Friedlander, Martin
Publicado no J Clin Invest (2016)

Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye

Por Michael, Iacovos P, Westenskow, Peter D, Hacibekiroglu, Sabiha, Greenwald, Alissa Cohen, Ballios, Brian G, Kurihara, Toshihide, Li, Zhijie, Warren, Carmen M, Zhang, Puzheng, Aguilar, Edith, Donaldson, Laura, Marchetti, Valentina, Baba, Takeshi, Hussein, Samer M, Sung, Hoon-Ki, Iruela-Arispe, M Luisa, Rini, James M, van der Kooy, Derek, Friedlander, Martin, Nagy, Andras
Publicado em 2014

MBNL proteins repress embryonic stem cell-specific alternative splicing and reprogramming

Por Han, Hong, Irimia, Manuel, Ross, P. Joel, Sung, Hoon-Ki, Alipanahi, Babak, David, Laurent, Golipour, Azadeh, Gabut, Mathieu, Michael, Iacovos P., Nachman, Emil N., Wang, Eric, Trcka, Dan, Thompson, Tadeo, O’Hanlon, Dave, Slobodeniuc, Valentina, Barbosa-Morais, Nuno L., Burge, Christopher B., Moffat, Jason, Frey, Brendan J., Nagy, Andras, Ellis, James, Wrana, Jeffrey L., Blencowe, Benjamin J.
Publicado em 2013