A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells

Lung carcinoids are variably aggressive and mechanistically understudied neuroendocrine neoplasms (NENs). Here, we identified and elucidated the function of a miR-375/yes-associated protein (YAP) axis in lung carcinoid (H727) cells. miR-375 and YAP are respectively high and low expressed in wild-typ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Xiaojing, Nanayakkara, Jina, Claypool, Duncan, Saghafinia, Sadegh, Wong, Justin J. M., Xu, Minqi, Wang, Xiantao, Nicol, Christopher J. B., Michael, Iacovos P., Hafner, Markus, Yang, Xiaolong, Renwick, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129150/
https://ncbi.nlm.nih.gov/pubmed/34001972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89855-4
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