Transcript expression levels of full-length alpha-synuclein and its three alternatively spliced variants in Parkinson’s disease brain regions and in a transgenic mouse model of alp...

по McLean, Jesse R., Hallett, Penelope J., Cooper, Oliver, Stanley, Michael, Isacson, Ole
Опубликовано 2011

Alpha-synuclein overexpressing transgenic mice show internal organ pathology and autonomic deficits

по Hallett, Penelope J, McLean, Jesse R, Kartunen, Andrew, Langston, J. William, Isacson, Ole
Опубликовано 2012

An Aggregate-Inducing Peripherin Isoform Generated through Intron Retention Is Upregulated in Amyotrophic Lateral Sclerosis and Associated with Disease Pathology

по Xiao, Shangxi, Tjostheim, Sonja, Sanelli, Teresa, McLean, Jesse R., Horne, Patrick, Fan, Yuxin, Ravits, John, Strong, Michael J., Robertson, Janice
Опубликовано в: J Neurosci (2008)

A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)

по Smith, Gaynor A., Rocha, Emily M., Rooney, Thomas, Barneoud, Pascal, McLean, Jesse R., Beagan, Jonathan, Osborn, Teresia, Coimbra, Madeleine, Luo, Yongyi, Hallett, Penelope J., Isacson, Ole
Опубликовано в: PLoS One (2015)

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

по Rocha, Emily M., Smith, Gaynor A., Park, Eric, Cao, Hongmei, Graham, Anne-Renee, Brown, Eilish, McLean, Jesse R., Hayes, Melissa A., Beagan, Jonathan, Izen, Sarah C., Perez-Torres, Eduardo, Hallett, Penelope J., Isacson, Ole
Опубликовано в: Antioxid Redox Signal (2015)

Jump from Pre-mutation to Pathologic Expansion in C9orf72

по Xi, Zhengrui, van Blitterswijk, Marka, Zhang, Ming, McGoldrick, Philip, McLean, Jesse R., Yunusova, Yana, Knock, Erin, Moreno, Danielle, Sato, Christine, McKeever, Paul M., Schneider, Raphael, Keith, Julia, Petrescu, Nicolae, Fraser, Paul, Tartaglia, Maria Carmela, Baker, Matthew C., Graff-Radford, Neill R., Boylan, Kevin B., Dickson, Dennis W., Mackenzie, Ian R., Rademakers, Rosa, Robertson, Janice, Zinman, Lorne, Rogaeva, Ekaterina
Опубликовано в: Am J Hum Genet (2015)

Familial Parkinson's disease iPSCs show cellular deficits in mitochondrial responses that can be pharmacologically rescued

по Cooper, Oliver, Seo, Hyemyung, Andrabi, Shaida, Guardia-Laguarta, Cristina, Graziotto, John, Sundberg, Maria, McLean, Jesse R., Carrillo-Reid, Luis, Xie, Zhong, Osborn, Teresia, Hargus, Gunnar, Deleidi, Michela, Lawson, Tristan, Bogetofte, Helle, Perez-Torres, Eduardo, Clark, Lorraine, Moskowitz, Carol, Mazzulli, Joseph, Chen, Li, Volpicelli-Daley, Laura, Romero, Norma, Jiang, Houbo, Uitti, Ryan J., Huang, Zhigao, Opala, Grzegorz, Scarffe, Leslie A., Dawson, Valina L., Klein, Christine, Feng, Jian, Ross, Owen A., Trojanowski, John Q., Lee, Virginia M.-Y., Marder, Karen, Surmeier, D. James, Wszolek, Zbigniew K., Przedborski, Serge, Krainc, Dimitri, Dawson, Ted M., Isacson, Ole
Опубликовано 2012