Targeting DNA repair with combination veliparib (ABT-888) and temozolomide in patients with metastatic castration-resistant prostate cancer

Autor Hussain, Maha, Carducci, Michael A., Slovin, Susan, Cetnar, Jeremy, Qian, Jiang, McKeegan, Evelyn M., Refici-Buhr, Marion, Chyla, Brenda, Shepherd, Stacie P., Giranda, Vincent L., Alumkal, Joshi J.
Vydáno v Invest New Drugs (2014)

Genetic biomarkers of sensitivity and resistance to venetoclax monotherapy in patients with relapsed acute myeloid leukemia

Autor Chyla, Brenda, Daver, Naval, Doyle, Kelly, McKeegan, Evelyn, Huang, Xin, Ruvolo, Vivian, Wang, Zixing, Chen, Ken, Souers, Andrew, Leverson, Joel, Potluri, Jalaja, Boghaert, Erwin, Bhathena, Anahita, Konopleva, Marina, Popovic, Relja
Vydáno v Am J Hematol (2018)

Phase I/II Study of Pemetrexed With or Without ABT-751 in Advanced or Metastatic Non–Small-Cell Lung Cancer

Autor Rudin, Charles M., Mauer, Ann, Smakal, Martin, Juergens, Rosalyn, Spelda, Stanislav, Wertheim, Michael, Coates, Andrew, McKeegan, Evelyn, Ansell, Peter, Zhou, Xiangdong, Qian, Jane, Pradhan, Rajendra, Dowell, Barry, Krivoshik, Andrew, Gordon, Gary
Vydáno v J Clin Oncol (2011)

EPT-15 A PHASE1/2 CLINICAL TRIAL OF VELIPARIB (ABT-888) AND RADIATION FOLLOWED BY MAINTENANCE THERAPY WITH VELIPARIB AND TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED DIFFUSE...

Autor Baxter, Patricia, Su, Jack, Li, Xiao-nan, Thomas, Arzu Onar, Billups, Catherine, Thompson, Patrick, Poussaint, Tina, McKeegan, Evelyn, Wan, Xia, Ansell, Peter, Giranda, Vincent, Paulino, Arnold, Kilburn, Lindsay, Qaddoumi, Ibrahim, Broniscer, Alberto, Blaney, Susan, Boyett, James, Fouladi, Maryam
Vydáno v Neuro Oncol (2016)

An open-label, phase 1 study evaluating safety, tolerability, and pharmacokinetics of linifanib (ABT-869) in Japanese patients with solid tumors

Autor Asahina, Hajime, Tamura, Yosuke, Nokihara, Hiroshi, Yamamoto, Noboru, Seki, Yoshitaka, Shibata, Takashi, Goto, Yasushi, Tanioka, Maki, Yamada, Yasuhide, Coates, Andrew, Chiu, Yi-Lin, Li, Xiaohui, Pradhan, Rajendra, Ansell, Peter J., McKeegan, Evelyn M., McKee, Mark D., Carlson, Dawn M., Tamura, Tomohide
Vydáno 2012

A phase I trial of veliparib (ABT-888) and temozolomide in children with recurrent CNS tumors: a Pediatric Brain Tumor Consortium report(†)

Autor Su, Jack M., Thompson, Patrick, Adesina, Adekunle, Li, Xiao-Nan, Kilburn, Lindsay, Onar-Thomas, Arzu, Kocak, Mehmet, Chyla, Brenda, McKeegan, Evelyn, Warren, Katherine E., Goldman, Stewart, Pollack, Ian F., Fouladi, Maryam, Chen, Alice, Giranda, Vincent, Boyett, James, Kun, Larry, Blaney, Susan M.
Vydáno v Neuro Oncol (2014)

Substantial Susceptibility of Chronic Lymphocytic Leukemia to BCL2 Inhibition: Results of a Phase I Study of Navitoclax in Patients With Relapsed or Refractory Disease

Autor Roberts, Andrew W., Seymour, John F., Brown, Jennifer R., Wierda, William G., Kipps, Thomas J., Khaw, Seong Lin, Carney, Dennis A., He, Simon Z., Huang, David C.S., Xiong, Hao, Cui, Yue, Busman, Todd A., McKeegan, Evelyn M., Krivoshik, Andrew P., Enschede, Sari H., Humerickhouse, Rod
Vydáno v J Clin Oncol (2012)

Efficacy and Biological Correlates of Response in a Phase 2 Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia

Autor Konopleva, Marina, Pollyea, Daniel A., Potluri, Jalaja, Chyla, Brenda, Hogdal, Leah, Busman, Todd, McKeegan, Evelyn, Salem, Ahmed Hamed, Zhu, Ming, Ricker, Justin L., Blum, William, DiNardo, Courtney D., Kadia, Tapan, Dunbar, Martin, Kirby, Rachel, Falotico, Nancy, Leverson, Joel, Humerickhouse, Rod, Mabry, Mack, Stone, Richard, Kantarjian, Hagop, Letai, Anthony
Vydáno v Cancer Discov (2016)

Phase I Study of Navitoclax (ABT-263), a Novel Bcl-2 Family Inhibitor, in Patients With Small-Cell Lung Cancer and Other Solid Tumors

Autor Gandhi, Leena, Camidge, D. Ross, Ribeiro de Oliveira, Moacyr, Bonomi, Philip, Gandara, David, Khaira, Divis, Hann, Christine L., McKeegan, Evelyn M., Litvinovich, Elizabeth, Hemken, Philip M., Dive, Caroline, Enschede, Sari H., Nolan, Cathy, Chiu, Yi-Lin, Busman, Todd, Xiong, Hao, Krivoshik, Andrew P., Humerickhouse, Rod, Shapiro, Geoffrey I., Rudin, Charles M.
Vydáno v J Clin Oncol (2011)

Randomized Phase II Study of Carboplatin and Paclitaxel With Either Linifanib or Placebo for Advanced Nonsquamous Non–Small-Cell Lung Cancer

Autor Ramalingam, Suresh S., Shtivelband, Mikhail, Soo, Ross A., Barrios, Carlos H., Makhson, Anatoly, Segalla, José G.M., Pittman, Kenneth B., Kolman, Petr, Pereira, Jose R., Srkalovic, Gordan, Belani, Chandra P., Axelrod, Rita, Owonikoko, Taofeek K., Qin, Qin, Qian, Jiang, McKeegan, Evelyn M., Devanarayan, Viswanath, McKee, Mark D., Ricker, Justin L., Carlson, Dawn M., Gorbunova, Vera A.
Vydáno v J Clin Oncol (2015)

Phase II Study of Single-Agent Navitoclax (ABT-263) and Biomarker Correlates in Patients with Relapsed Small Cell Lung Cancer

Autor Rudin, Charles M., Hann, Christine L., Garon, Edward B., Ribeiro de Oliveira, Moacyr, Bonomi, Philip D., Camidge, D. Ross, Chu, Quincy, Giaccone, Giuseppe, Khaira, Divis, Ramalingam, Suresh S., Ranson, Malcolm R., Dive, Caroline, McKeegan, Evelyn M., Chyla, Brenda J., Dowell, Barry L., Chakravartty, Arunava, Nolan, Cathy E., Rudersdorf, Niki, Busman, Todd A., Mabry, Mack H., Krivoshik, Andrew P., Humerickhouse, Rod A., Shapiro, Geoffrey I., Gandhi, Leena
Vydáno 2012