Amyotrophic Lateral Sclerosis–Plus Syndrome With TAR DNA-Binding Protein-43 Pathology

Por McCluskey, Leo F., Elman, Lauren B., Martinez-Lage, Maria, Van Deerlin, Vivianna, Yuan, Wuxing, Clay, Dana, Siderowf, Andrew, Trojanowski, John Q.
Publicado em 2009

Quantitative proton magnetic resonance spectroscopy detects abnormalities in dorsolateral prefrontal cortex and motor cortex of patients with frontotemporal lobar degeneration

Por Chawla, Sanjeev, Wang, Sumei, Moore, Peachie, Woo, John H., Elman, Lauren, McCluskey, Leo F., Melhem, Elias R., Grossman, Murray, Poptani, Harish
Publicado em 2009

Whole-Brain Analysis of Amyotrophic Lateral Sclerosis by Using Echo-Planar Spectroscopic Imaging

Por Verma, Gaurav, Woo, John H., Chawla, Sanjeev, Wang, Sumei, Sheriff, Sulaiman, Elman, Lauren B., McCluskey, Leo F., Grossman, Murray, Melhem, Elias R., Maudsley, Andrew A., Poptani, Harish
Publicado em 2013

Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy

Por Geser, Felix, Stein, Beth, Partain, Michael, Elman, Lauren B., McCluskey, Leo F., Xie, Sharon X., Van Deerlin, Vivianna M., Kwong, Linda K., Lee, Virginia M.-Y., Trojanowski, John Q.
Publicado em 2011

Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U

Por Lee, Edward B, Russ, Jenny, Jung, Hyunjoo, Elman, Lauren B, Chahine, Lama M, Kremens, Daniel, Miller, Bruce L, Coslett, H Branch, Trojanowski, John Q, Van Deerlin, Vivianna M, McCluskey, Leo F
Publicado em 2013

Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases

Por Sheinerman, Kira S., Toledo, Jon B., Tsivinsky, Vladimir G., Irwin, David, Grossman, Murray, Weintraub, Daniel, Hurtig, Howard I., Chen-Plotkin, Alice, Wolk, David A., McCluskey, Leo F., Elman, Lauren B., Trojanowski, John Q., Umansky, Samuil R.
Publicado no Alzheimers Res Ther (2017)

Enrichment of C-Terminal Fragments in TAR DNA-Binding Protein-43 Cytoplasmic Inclusions in Brain but not in Spinal Cord of Frontotemporal Lobar Degeneration and Amyotrophic Lateral...

Por Igaz, Lionel M., Kwong, Linda K., Xu, Yan, Truax, Adam C., Uryu, Kunihiro, Neumann, Manuela, Clark, Christopher M., Elman, Lauren B., Miller, Bruce L., Grossman, Murray, McCluskey, Leo F., Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado em 2008

Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration

Por Suh, EunRan, Lee, Edward B., Neal, Donald, Wood, Elisabeth M., Toledo, Jon B., Rennert, Lior, Irwin, David J., McMillan, Corey T., Krock, Bryan, Elman, Lauren B., McCluskey, Leo F., Grossman, Murray, Xie, Sharon X., Trojanowski, John Q., Van Deerlin, Vivianna M.
Publicado no Acta Neuropathol (2015)

Cognitive decline and reduced survival in C9orf72 expansion Frontotemporal degeneration and Amyotrophic lateral sclerosis

Por Irwin, David J., McMillan, Corey T., Brettschneider, Johannes, Libon, David J., Powers, John, Rascovsky, Katya, Toledo, Jon B., Boller, Ashley, Bekisz, Jonathan, Chandrasekaran, Keerthi, Wood, Elisabeth McCarty, Shaw, Leslie M., Woo, John H., Cook, Philip A., Wolk, David A., Arnold, Steven E., Van Deerlin, Vivianna M., McCluskey, Leo F., Elman, Lauren, Lee, Virginia M.-Y., Trojanowski, John Q., Grossman, Murray
Publicado em 2012

Defining SOD1 ALS natural history to guide therapeutic clinical trial design

Por Bali, Taha, Self, Wade, Liu, Jingxia, Siddique, Teepu, Wang, Leo H, Bird, Thomas D, Ratti, Elena, Atassi, Nazem, Boylan, Kevin B, Glass, Jonathan D, Maragakis, Nicholas J, Caress, James B, McCluskey, Leo F, Appel, Stanley H, Wymer, James P, Gibson, Summer, Zinman, Lorne, Mozaffar, Tahseen, Callaghan, Brian, McVey, April L, Jockel-Balsarotti, Jennifer, Allred, Peggy, Fisher, Elena R, Lopate, Glenn, Pestronk, Alan, Cudkowicz, Merit E, Miller, Timothy M
Publicado no J Neurol Neurosurg Psychiatry (2016)

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis

Por Gendron, Tania F., Chew, Jeannie, Stankowski, Jeannette N., Hayes, Lindsey R., Zhang, Yong-Jie, Prudencio, Mercedes, Carlomagno, Yari, Daughrity, Lillian M., Jansen-West, Karen, Perkerson, Emilie A., O’Raw, Aliesha, Cook, Casey, Pregent, Luc, Belzil, Veronique, van Blitterswijk, Marka, Tabassian, Lilia J., Lee, Chris W., Yue, Mei, Tong, Jimei, Song, Yuping, Castanedes-Casey, Monica, Rousseau, Linda, Phillips, Virginia, Dickson, Dennis W., Rademakers, Rosa, Fryer, John D., Rush, Beth K., Pedraza, Otto, Caputo, Ana M., Desaro, Pamela, Palmucci, Carla, Robertson, Amelia, Heckman, Michael G., Diehl, Nancy N., Wiggs, Edythe, Tierney, Michael, Braun, Laura, Farren, Jennifer, Lacomis, David, Ladha, Shafeeq, Fournier, Christina N., McCluskey, Leo F., Elman, Lauren B., Toledo, Jon B., McBride, Jennifer D., Tiloca, Cinzia, Morelli, Claudia, Poletti, Barbara, Solca, Federica, Prelle, Alessandro, Wuu, Joanne, Jockel-Balsarotti1, Jennifer, Rigo, Frank, Ambrose, Christine, Datta, Abhishek, Yang, Weixing, Raitcheva, Denitza, Antognetti, Giovanna, McCampbell, Alexander, Van Swieten, John C., Miller, Bruce L., Boxer, Adam L., Brown, Robert H., Bowser, Robert, Miller, Timothy M., Trojanowski, John Q., Grossman, Murray, Berry, James D., Hu, William T., Ratti, Antonia, Traynor, Bryan J., Disney, Matthew D., Benatar, Michael, Silani, Vincenzo, Glass, Jonathan D., Floeter, Mary Kay, Rothstein, Jeffrey D., Boylan, Kevin B., Petrucelli, Leonard
Publicado no Sci Transl Med (2017)