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Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy

Motor neuron disease (MND) may present as an isolated lower motor neuron (LMN) disorder. Although the significance of pathological 43 kDa transactive responsive sequence DNA binding protein (TDP-43) for amyotrophic lateral sclerosis (ALS) was appreciated only recently, the topographical distribution...

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Detalhes bibliográficos
Main Authors: Geser, Felix, Stein, Beth, Partain, Michael, Elman, Lauren B., McCluskey, Leo F., Xie, Sharon X., Van Deerlin, Vivianna M., Kwong, Linda K., Lee, Virginia M.-Y., Trojanowski, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125638/
https://ncbi.nlm.nih.gov/pubmed/21225272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0797-z
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