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Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy
Motor neuron disease (MND) may present as an isolated lower motor neuron (LMN) disorder. Although the significance of pathological 43 kDa transactive responsive sequence DNA binding protein (TDP-43) for amyotrophic lateral sclerosis (ALS) was appreciated only recently, the topographical distribution...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125638/ https://ncbi.nlm.nih.gov/pubmed/21225272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0797-z |
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