Management of Amyotrophic Lateral Sclerosis

Por Bali, Taha, Miller, Timothy M.
Publicado no Mo Med (2013)

RNA-targeted Therapeutics for ALS

Por Reddy, Linga V., Miller, Timothy M.
Publicado no Neurotherapeutics (2015)

Antisense oligonucleotides: Translation from mouse models to human neurodegenerative diseases

Por Schoch, Kathleen M., Miller, Timothy M.
Publicado no Neuron (2017)

Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System

Por DeVos, Sarah L., Miller, Timothy M.
Publicado em 2013

Antisense Oligonucleotides: Treating Neurodegeneration at the Level of RNA

Por DeVos, Sarah L., Miller, Timothy M.
Publicado em 2013

Canine Degenerative Myelopathy: Biochemical characterization of superoxide dismutase 1 in the first naturally occurring non-human amyotrophic lateral sclerosis model()

Por Crisp, Matthew J., Beckett, Jeffrey, Coates, Joan R., Miller, Timothy M.
Publicado em 2013

Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria

Por Vande Velde, Christine, Miller, Timothy M., Cashman, Neil R., Cleveland, Don W.
Publicado em 2008

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

Por Wegorzewska, Iga, Bell, Shaughn, Cairns, Nigel J., Miller, Timothy M., Baloh, Robert H.
Publicado em 2009

RCADiA: Simple Automation Platform for Comparative Multidimensional Protein Identification (MuDPIT)

Por Bailey, Aaron O., Miller, Timothy M., Dong, Meng-Qiu, Velde, Christine Vande, Cleveland, Don W., Yates, John R.
Publicado em 2007

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

Por Kanekura, Kohsuke, Yagi, Takuya, Cammack, Alexander J., Mahadevan, Jana, Kuroda, Masahiko, Harms, Matthew B., Miller, Timothy M., Urano, Fumihiko
Publicado no Hum Mol Genet (2016)

Virus-Delivered Small RNA Silencing Sustains Strength in Amyotrophic Lateral Sclerosis

Por Miller, Timothy M., Kaspar, Brian K., Kops, Geert J., Yamanaka, Koji, Christian, Lindsey J., Gage, Fred H., Cleveland, Don W.
Publicado em 2005

Bax Deletion Further Orders the Cell Death Pathway in Cerebellar Granule Cells and Suggests a Caspase-independent Pathway to Cell Death

Por Miller, Timothy M., Moulder, Krista L., Knudson, C. Michael, Creedon, Douglas J., Deshmukh, Mohanish, Korsmeyer, Stanley J., Johnson, Eugene M.
Publicado em 1997

Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice

Por Koval, Erica D., Shaner, Carey, Zhang, Peter, du Maine, Xavier, Fischer, Kimberlee, Tay, Jia, Chau, B. Nelson, Wu, Gregory F., Miller, Timothy M.
Publicado em 2013

ALS onset is influenced by the burden of rare variants in known ALS genes

Por Cady, Janet, Allred, Peggy, Bali, Taha, Pestronk, Alan, Goate, Alison, Miller, Timothy M., Mitra, Rob, Ravits, John, Harms, Matthew B., Baloh, Robert H.
Publicado no Ann Neurol (2014)

Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo

Por Kaufman, Sarah K., Sanders, David W., Thomas, Talitha L., Ruchinskas, Allison, Vaquer-Alicea, Jaime, Sharma, Apurwa M., Miller, Timothy M., Diamond, Marc I.
Publicado no Neuron (2016)

Pre-morbid Type 2 Diabetes Mellitus is not a prognostic factor in ALS

Por Paganoni, Sabrina, Hyman, Theodore, Shui, Amy, Allred, Peggy, Harms, Matthew, Liu, Jingxia, Maragakis, Nicholas, Schoenfeld, David, Yu, Hong, Atassi, Nazem, Cudkowicz, Merit, Miller, Timothy M.
Publicado no Muscle Nerve (2015)

Synthesis and in vitro characterization of a P2X7 radioligand [(123)I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer Disease

Por Jin, Hongjun, Han, Junbin, Resing, Derek, Liu, Hui, Yue, Xuyi, Miller, Rebecca L., Schoch, Kathleen M., Miller, Timothy M., Perlmutter, Joel S., Egan, Terrance M., Tu, Zhude
Publicado no Eur J Pharmacol (2017)

MicroRNA signature of central nervous system‐infiltrating dendritic cells in an animal model of multiple sclerosis

Por Hoye, Mariah L., Archambault, Angela S., Gordon, Taylor M., Oetjen, Landon K., Cain, Matthew D., Klein, Robyn S., Crosby, Seth D., Kim, Brian S., Miller, Timothy M., Wu, Gregory F.
Publicado no Immunology (2018)

Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis

Por Miller, Timothy M., Kim, Soo H., Yamanaka, Koji, Hester, Mark, Umapathi, Priya, Arnson, Hannah, Rizo, Liza, Mendell, Jerry R., Gage, Fred H., Cleveland, Don W., Kaspar, Brian K.
Publicado em 2006

Protein production is an early biomarker for RNA‐targeted therapies

Por Self, Wade K., Schoch, Kathleen M., Alex, Jacob, Barthélemy, Nicolas, Bollinger, James G., Sato, Chihiro, Cole, Tracy, Kordasiewicz, Holly B., Swayze, Eric, Bateman, Randall J., Miller, Timothy M.
Publicado no Ann Clin Transl Neurol (2018)