Differential Effects of DNA Double-Strand Break Repair Pathways on Single-Strand and Self-Complementary Adeno-Associated Virus Vector Genomes

Por Cataldi, Marcela P., McCarty, Douglas M.
Publicado em 2010

Hairpin end conformation of adeno-associated virus (AAV) genome determines interactions with DNA repair pathways

Por Cataldi, Marcela P., McCarty, Douglas M.
Publicado em 2012

Effects of Adeno-Associated Virus DNA Hairpin Structure on Recombination

Por Choi, Vivian W., Samulski, R. Jude, McCarty, Douglas M.
Publicado em 2005

AAV Hybrid Serotypes: Improved Vectors for Gene Delivery

Por Choi, Vivian W., McCarty, Douglas M., Samulski, R. Jude
Publicado em 2005

Host Cell DNA Repair Pathways in Adeno-Associated Viral Genome Processing

Por Choi, Vivian W., McCarty, Douglas M., Samulski, R. Jude
Publicado em 2006

Roles of Adeno-Associated Virus Rep Protein and Human Chromosome 19 in Site-Specific Recombination

Por Young, Samuel M., McCarty, Douglas M., Degtyareva, Natalya, Samulski, Richard Jude
Publicado em 2000

Peripheral Nervous System Neuropathology and Progressive Sensory Impairments in a Mouse Model of Mucopolysaccharidosis IIIB

Por Fu, Haiyan, Bartz, Julianne D., Stephens, Robert L., McCarty, Douglas M.
Publicado em 2012

Correction of Neurological Disease of Mucopolysaccharidosis IIIB in Adult Mice by rAAV9 Trans-Blood–Brain Barrier Gene Delivery

Por Fu, Haiyan, DiRosario, Julianne, Killedar, Smruti, Zaraspe, Kimberly, McCarty, Douglas M
Publicado em 2011

Near-Complete Correction of Profound Metabolomic Impairments Corresponding to Functional Benefit in MPS IIIB Mice after IV rAAV9-hNAGLU Gene Delivery

Por Fu, Haiyan, Meadows, Aaron S., Ware, Tierra, Mohney, Robert P., McCarty, Douglas M.
Publicado no Mol Ther (2017)

Development and Characterization of Novel Empty Adenovirus Capsids and Their Impact on Cellular Gene Expression

Por Stilwell, Jackie L., McCarty, Douglas M., Negishi, Atsuko, Superfine, Richard, Samulski, R. Jude
Publicado em 2003

Mucopolysaccharidosis IIIB, a lysosomal storage disease, triggers a pathogenic CNS autoimmune response

Por Killedar, Smruti, DiRosario, Julianne, Divers, Erin, Popovich, Phillip G, McCarty, Douglas M, Fu, Haiyan
Publicado em 2010

Effective Depletion of Pre-existing Anti-AAV Antibodies Requires Broad Immune Targeting

Por Velazquez, Victoria M., Meadows, Aaron S., Pineda, Ricardo J., Camboni, Marybeth, McCarty, Douglas M., Fu, Haiyan
Publicado no Mol Ther Methods Clin Dev (2017)

Limited Entry of Adenovirus Vectors into Well-Differentiated Airway Epithelium Is Responsible for Inefficient Gene Transfer

Por Pickles, Raymond J., McCarty, Douglas, Matsui, Hirotoshi, Hart, Pádraig J., Randell, Scott H., Boucher, Richard C.
Publicado em 1998

Patterns of scAAV Vector Insertion Associated With Oncogenic Events in a Mouse Model for Genotoxicity

Por Rosas, Lucia E, Grieves, Jessica L, Zaraspe, Kimberly, La Perle, Krista MD, Fu, Haiyan, McCarty, Douglas M
Publicado em 2012

Amyloidosis, Synucleinopathy, and Prion Encephalopathy in a Neuropathic Lysosomal Storage Disease: The CNS-Biomarker Potential of Peripheral Blood

Por Naughton, Bartholomew J., Duncan, F. Jason, Murrey, Darren, Ware, Tierra, Meadows, Aaron, McCarty, Douglas M., Fu, Haiyan
Publicado em 2013

Rapid Transgene Expression in Multiple Precursor Cell Types of Adult Rat Subventricular Zone Mediated by Adeno-Associated Type 1 Vectors

Por Bockstael, Olivier, Melas, Catherine, Pythoud, Catherine, Levivier, Marc, McCarty, Douglas, Samulski, R. Jude, De Witte, Olivier, Tenenbaum, Liliane
Publicado em 2012

Functional correction of neurological and somatic disorders at later stages of disease in MPS IIIA mice by systemic scAAV9-hSGSH gene delivery

Por Fu, Haiyan, Cataldi, Marcela P, Ware, Tierra A, Zaraspe, Kimberly, Meadows, Aaron S, Murrey, Darren A, McCarty, Douglas M
Publicado no Mol Ther Methods Clin Dev (2016)

Differential distribution of heparan sulfate glycoforms and elevated expression of heparan sulfate biosynthetic enzyme genes in the brain of mucopolysaccharidosis IIIB mice

Por McCarty, Douglas M., DiRosario, Julianne, Gulaid, Kadra, Killedar, Smruti, Oosterhof, Arie, van Kuppevelt, Toin H., Martin, Paul T., Fu, Haiyan
Publicado em 2011

Intrathecal long-term gene expression by self-complementary adeno-associated virus type 1 suitable for chronic pain studies in rats

Por Storek, Benjamin, Harder, Nina M, Banck, Michaela S, Wang, Cheng, McCarty, Douglas M, Janssen, William GM, Morrison, John H, Walsh, Christopher E, Beutler, Andreas S
Publicado em 2006

Broad Functional Correction of Molecular Impairments by Systemic Delivery of scAAVrh74-hSGSH Gene Delivery in MPS IIIA Mice

Por Duncan, F Jason, Naughton, Bartholomew J, Zaraspe, Kimberly, Murrey, Darren A, Meadows, Aaron S, Clark, Kelly Reed, Newsom, David E, White, Peter, Fu, Haiyan, McCarty, Douglas M
Publicado no Mol Ther (2015)