Mucopolysaccharidosis IIIB, a lysosomal storage disease, triggers a pathogenic CNS autoimmune response

BACKGROUND: Recently, using a mouse model of mucopolysaccharidosis (MPS) IIIB, a lysosomal storage disease with severe neurological deterioration, we showed that MPS IIIB neuropathology is accompanied by a robust neuroinflammatory response of unknown consequence. This study was to assess whether MPS...

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Autori principali: Killedar, Smruti, DiRosario, Julianne, Divers, Erin, Popovich, Phillip G, McCarty, Douglas M, Fu, Haiyan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914668/
https://ncbi.nlm.nih.gov/pubmed/20637096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-39
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